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Merck

C7821

Sigma-Aldrich

Curdlan

from Alcaligenes faecalis, ≥98% (TLC), solid

别名:

β-1,3-葡聚糖 水合物

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

产品名称

热凝胶多糖 来源于粪产碱菌,

形狀

solid

品質等級

儲存溫度

2-8°C

一般說明

凝胶多糖是一种线性结构的不溶性天然聚合物,主要由粪产碱菌产生。它是一种具有明胶特性的膳食纤维。

應用

来自粪产碱菌的凝胶多糖已用于:
  • 刺激鲤鱼巨噬细胞,以调节差异表达基因
  • 刺激人肠上皮细胞分泌细胞因子
  • 研究其对小鼠肺泡巨噬细胞炎症/呼吸爆发相关基因转录反应的影响
  • 在β-1,3–1,4-葡聚糖酶活性检测中用作底物

生化/生理作用

凝胶多糖在食品工业中=用作食品添加剂。它可以提高羟基磷灰石/壳聚糖支架的弹性,降低了易脆性,有助于骨再生。
热凝胶多糖是一种(1,3)-β-葡聚糖。它是由受体dectin-1识别的病原体相关分子模式(PAMP)。激活的dectin-1与TLR2/TLR6一起可促进信号传导,导致促炎细胞因子的产生,从而诱导炎症。

準備報告

对于70℃条件下的凝胶化,氢氧化钠的浓度应为0.01M。
This product is tested for solubility in 0.1N sodium hydroxide at a concentration of 9.8 - 10.2 mg/mL. Heating and/or sonication are typically required for solubilization. This product is not sterile. For use in cell culture, stock solutions should be filter sterilized prior to use.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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Characterisation of a novel Bacillus sp. SJ-10 I?-1,3-1,4-glucanase isolated from jeotgal, a traditional Korean fermented fish.
Kim, et al.
Bioprocess and Biosystems Engineering, 36, 721-727 (2013)
Chunju An et al.
The Journal of biological chemistry, 284(29), 19716-19726 (2009-06-03)
Serine proteinases in insect plasma have been implicated in two types of immune responses; that is, activation of prophenoloxidase (proPO) and activation of cytokine-like proteins. We have identified more than 20 serine proteinases in hemolymph of the tobacco hornworm, Manduca
K N Masihi et al.
International journal of immunopharmacology, 19(9-10), 463-468 (1998-06-24)
The effects of glucan-based immunomodulators curdlan sulfate (CRDS) and lentinan on cytokine production stimulated by lipopolysaccharide (LPS) in bacillus Calmette-Guerin (BCG)-primed mice were investigated. Pretreatment with CRDS or lentinan before LPS administration induced a striking inhibition of up to 89%
Nicola Jackson et al.
European journal of immunology, 44(4), 962-969 (2014-01-25)
Type B T cells recognize peptide-MHC class II (pMHCII) isoforms that are structurally distinct from those recognized by conventional type A T cells. These alternative type B conformers result from peptide loading in the absence of HLA-DM. Type A conformers
M Matsushita
Immunology letters, 26(1), 95-97 (1990-10-01)
From the results of consumption experiments of guinea pig complement, Curdlan, a (1----3)-beta-D-glucan obtained from Alcaligenes faecalis var. myxogenes IFO13140, has been found to lack the ability to activate complement when unheated or preheated at either 40 degrees C or

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