C5874
Cidofovir hydrate
≥98% (HPLC), powder, viral DNA synthesis inhibitor
别名:
(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, (S)-HPMPC; Cidovir, HPMPC, Vistide
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所有图片(1)
About This Item
经验公式（希尔记法）:
C8H14N3O6P · xH2O
CAS号:
分子量:
279.19 (anhydrous basis)
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
产品名称
Cidofovir hydrate, ≥98% (HPLC)
品質等級
化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
protect from light
溶解度
deionized water: ≥5 mg/mL (warmed)
儲存溫度
room temp
SMILES 字串
O.NC1=NC(=O)N(C[C@@H](CO)OCP(O)(O)=O)C=C1
InChI
1S/C8H14N3O6P.H2O/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16;/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16);1H2/t6-;/m0./s1
InChI 密鑰
KLJYJZIIJLYJNN-RGMNGODLSA-N
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生化／生理作用
Selective inhibitor of viral DNA synthesis through the selective inhibition of viral DNA polymerase.
特點和優勢
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Skin Irrit. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Ryan N Jennings et al.
Journal of virology, 88(24), 14040-14049 (2014-09-26)
CD8(+) T cell responses are critical to the control of replication and reactivation associated with gammaherpesvirus infection. Type I interferons (IFNs) have been shown to have direct and indirect roles in supporting CD8(+) T cell development and function during viral
Jonathan Schelfhout et al.
Current medical research and opinion, 36(1), 43-50 (2019-09-07)
Objective: This study utilized a large, national US database to explore the impact of Cytomegalovirus (CMV) infection on hospital services utilization and costs during the first 100 days following allogeneic hematopoietic stem cell transplant (allo-HSCT).Methods: This retrospective, observational cohort study used
Joanna Jackowska et al.
Lasers in medical science, 34(7), 1433-1440 (2019-02-15)
Mechanical debulking of laryngeal papillomas is associated with voice disorders due to impairment of the vocal fold's mucosa. Intraepithelial injection of cidofovir reduces damage to the laryngeal structures and thus improves vocal parameters. The aim of our study was to
Successful treatment of perianal giant condyloma acuminatum in an immunocompromised host with systemic interleukin 2 and topical cidofovir.
Vinod E Nambudiri et al.
JAMA dermatology, 149(9), 1068-1070 (2013-07-05)
Stephen D S McCarthy et al.
PLoS neglected tropical diseases, 10(1), e0004364-e0004364 (2016-01-12)
To date there are no approved antiviral drugs for the treatment of Ebola virus disease (EVD). While a number of candidate drugs have shown limited efficacy in vitro and/or in non-human primate studies, differences in experimental methodologies make it difficult
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