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About This Item
经验公式（希尔记法）:
C16H17N3O4S · xH2O
CAS号:
分子量:
347.39 (anhydrous basis)
Beilstein:
965503
EC號碼:
MDL號碼:
分類程式碼代碼:
51282503
PubChem物質ID:
NACRES:
NA.85
推荐产品
形狀
powder
pKa
5.2
7.3
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
作用方式
cell wall synthesis | interferes
儲存溫度
2-8°C
SMILES 字串
S1C2N(C(=C(C1)C)C(=O)O)C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3.O
InChI
1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15?;/m1./s1
InChI 密鑰
AVGYWQBCYZHHPN-FNOHQHCYSA-N
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一般說明
Chemical structure: ß-lactam
應用
Cephalexin is a cephalosporin antibiotic used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
生化／生理作用
Cephalexin disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cephalexin antibiotics mimic the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan.
其他說明
Storage of this product should be in airtight containers and protected from light.
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1 - Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
其他客户在看
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American journal of physiology. Gastrointestinal and liver physiology, 305(10), G678-G684 (2013-09-28)
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William T Gray et al.
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