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Merck

C0609

Sigma-Aldrich

鼠尾草酸 来源于迷迭香

≥91%, powder

别名:

(4AR,10aS)-5,6-二羟基-1,1-二甲基-7-丙-2-基-2,3,4,9,10,10a-六氢萘-4a-羧酸

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About This Item

经验公式(希尔记法):
C20H28O4
CAS号:
分子量:
332.43
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.25

品質等級

化驗

≥91%

形狀

powder

顏色

faintly yellow to dark yellow

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C(O)=O)c2c(O)c1O

InChI

1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1

InChI 密鑰

QRYRORQUOLYVBU-VBKZILBWSA-N

相关类别

應用

来源于迷迭香的鼠尾草酸主要用于研究其作为抗氧化剂的机制如何防止脂质过氧化和蛋白质羰基化。可用于评估鼠尾草酸的神经保护活性,包括它调节 6-羟基多巴胺(6-OHDA)的神经毒性作用的能力。也可用于研究其抗癌潜力。
酚类化合物,天然具有抗氧化特性。抑制由 NADH 或 NADPH 氧化引起的脂质过氧化。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tayebeh Rezaie et al.
Investigative ophthalmology & visual science, 53(12), 7847-7854 (2012-10-20)
The herb rosemary has been reported to have antioxidant and anti-inflammatory activity. We have previously shown that carnosic acid (CA), present in rosemary extract, crosses the blood-brain barrier to exert neuroprotective effects by upregulating endogenous antioxidant enzymes via the Nrf2
Linda Saxe Einbond et al.
Fitoterapia, 83(7), 1160-1168 (2012-07-26)
Studies indicate that extracts and purified components, including carnosic acid, from the herb rosemary display significant growth inhibitory activity on a variety of cancers. This paper examines the ability of rosemary/carnosic acid to inhibit the growth of human breast cancer
Kishor S Jain et al.
Bioorganic & medicinal chemistry, 15(14), 4674-4699 (2007-05-25)
Coronary arterial diseases are responsible for more deaths than all other associated causes combined. Elevated serum cholesterol levels leading to atherosclerosis can cause coronary heart disease (CHD). Reduction in serum cholesterol levels reduces the risk for CHD, substantially. Medicinal chemists
Carnosic acid attenuates lipopolysaccharide-induced liver injury in rats via fortifying cellular antioxidant defense system.
Xiang Q, Liu Z, Wang Y, Xiao H, et al.
Food And Chemical Toxicology (2012)
A I Kuzmenko et al.
Journal of photochemistry and photobiology. B, Biology, 48(1), 63-67 (1999-04-17)
Lipid free-radical oxidation has been studied in vivo in the mitochondrial fractions of the liver of rats fed RoseOx (carnosic acid nutritional supplement) by measuring chemiluminescence. The kinetics of the lipid chemiluminescence in rats fed RoseOx are significantly different from

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