推荐产品
product name
Arachidonoyl-AMC, fatty acid amide hydrolase substrate
品質等級
化驗
99% (HPLC)
形狀
solid
儲存條件
under inert gas
溶解度
DMSO: soluble
儲存溫度
−20°C
SMILES 字串
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)Nc1ccc2C(C)=CC(=O)Oc2c1
InChI
1S/C30H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-29(32)31-26-21-22-27-25(2)23-30(33)34-28(27)24-26/h7-8,10-11,13-14,16-17,21-24H,3-6,9,12,15,18-20H2,1-2H3,(H,31,32)/b8-7-,11-10-,14-13-,17-16-
InChI 密鑰
IQPBUDMTXHWSHB-ZKWNWVNESA-N
應用
Fluorogenic substrate used in a selective and sensitive assay of fatty acid amide hydrolase (FAAH).
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Simona Di Martino et al.
Journal of medicinal chemistry, 63(7), 3634-3664 (2020-03-17)
Sphingolipids (SphLs) are a diverse class of molecules that are regulated by a complex network of enzymatic pathways. A disturbance in these pathways leads to lipid accumulation and initiation of several SphL-related disorders. Acid ceramidase is one of the key
Enrico Dainese et al.
Scientific reports, 10(1), 2292-2292 (2020-02-12)
Fatty acid amide hydrolase (FAAH) is a membrane-bound homodimeric enzyme that in vivo controls content and biological activity of N-arachidonoylethanolamine (AEA) and other relevant bioactive lipids termed endocannabinoids. Parallel orientation of FAAH monomers likely allows both subunits to simultaneously recruit
Xinwen Zhang et al.
Neuropharmacology, 128, 269-281 (2017-10-25)
Monoacylglycerol lipase (MGL) hydrolyzes 2-arachidonoylglycerol to arachidonic acid and glycerol. Inhibition of MGL may attenuate neuroinflammation by enhancing endocannabinoid signaling and decreasing prostaglandin (PG) production. Almost half of HIV infected individuals are afflicted with HIV-associated neurocognitive disorder (HAND), a neuroinflammatory
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