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257370

Sigma-Aldrich

7-氨基-4-甲基香豆素

99%

别名:

香豆素 120

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About This Item

经验公式（希尔记法）:
C10H9NO2
CAS号:
26093-31-2
分子量:
175.18
Beilstein:
142231
EC號碼:
247-454-8
MDL號碼:
MFCD00006868
分類程式碼代碼:
12352103
PubChem物質ID:
57648146
NACRES:
NA.23

描述

chromophore for enzyme substrates

化驗

99%

形狀

solid

mp

223-226 °C (lit.)

λmax

354 nm in ethanol

儲存溫度

2-8°C

SMILES 字串

CC1=CC(=O)Oc2cc(N)ccc12

InChI

1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3

InChI 密鑰

GLNDAGDHSLMOKX-UHFFFAOYSA-N

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相关类别

一般說明

7-氨基-4-甲基香豆素（香豆素120）是一种氨基香豆素激光染料，可发出370-760 nm范围内的激光。它含有三个C-H···O和N-H····O分子间氢键结构。

應用

香豆素120可作为荧光标记试剂，用于痕量酶的测定。由于它可影响细胞形态，因而可用作抗结核分枝杆菌MDR分离株的抗菌剂。香豆素120也可用作电子供体（氨基），以转移荧光传感器中的电荷，以检测水性介质中的汞离子。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000295811
0000295812
0000295811
0000295812
SLCK8063

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Fluorescence quenching of 7-amino-4-methylcoumarin by different TEMPO derivatives.
Zamojc K, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 136(12), 1875-1880 (2015)
7-Amino-4-methylcoumarin.
Jasinski J and Woudenberg R
Acta Crystallographica Section C, Crystal Structure Communications, 50(12), 1954-1956 (1994)
A ?turn-on? coumarin-based fluorescent sensor with high selectivity for mercury ions in aqueous media.
Voutsadaki S, et al.
Chemical Communications (Cambridge, England), 46(19), 3292-3294 (2010)
Aldrichimica Acta, 15, 42-42 (1982)
Sander S van Berkel et al.
ChemMedChem, 7(4), 606-617 (2012-02-02)
The synthesis of a series of peptides containing C-terminal 7-amino-4-methylcoumarin (AMC) for use in the thrombin generation test (TGT) is described. The lead structure in this project was H-Gly-Gly-Arg-AMC, of which the water solubility and kinetic parameters (K(M) and k(cat))
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