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Merck

A6132

Sigma-Aldrich

三磷酸腺苷双磷酸酶 来源于马铃薯

ATPase ≥3.0 units/mg protein, lyophilized powder

别名:

腺苷5′-三磷酸酶, 腺苷5′-二磷酸酶

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About This Item

CAS号:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

生物源

potato

品質等級

種類

Grade I

形狀

lyophilized powder

ATPase activity

≥3.0 units/mg protein

成份

Protein, 30-60%

儲存溫度

−20°C

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應用

三磷酸腺苷双磷酸酶被用于水解核苷三磷酸和二磷酸。Sigma的三磷酸腺苷双磷酸酶已被用于血小板聚集的抑制研究
不同种类的马铃薯(S. tuberosum)中存在至少2种同工酶:一种的ATP酶/ADP酶比例较高(∼10)和另一种较低(∼1)。
反应:ATP → ADP+Pi → AMP+2Pi

生化/生理作用

三磷酸腺苷双磷酸酶存在于所有真核生物和一些原核生物中。来自马铃薯的三磷酸腺苷双磷酸酶在调节生长和发育中具有至关重要的作用。三磷酸腺苷双磷酸酶参与突触ATP(神经刺激后的神经递质)的失活以及抑制ADP诱导的血小板聚集以防止血栓形成。其发挥活性需要二价金属离子,并且在使用5 mM钙离子时观察到最佳活性。

包裝

按 ATP 酶单位销售。

其他說明

高比率和低比率同工酶混合物。

單位定義

一个酶活性单位是指在pH 6.5、30℃下,每分钟释放1.0μM无机磷所需的酶量

外觀

部分纯化的冻干粉末,含有琥珀酸钾

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Resp. Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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V T Nachmias et al.
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Nucleoside triphosphate diphosphohydrolases (NTPDases; apyrases) (EC 3.6.1.5) hydrolyze di- and triphosphate nucleotides, but not monophosphate nucleotides. They are categorized as E-type ATPases, have a broad divalent cation (Mg(2+), Ca(2+)) requirement for activation and are insensitive to inhibitors of F-type, P-type

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