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Merck

A4599

SAFC

L -精氨酸 单盐酸盐

制药生产

别名:

(S)-(+)-2-氨基-5-[(氨基亚甲基)氨基]戊酸 单盐酸盐, (S)-(+)-精氨酸 盐酸盐

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About This Item

经验公式(希尔记法):
C6H14N4O2 · HCl
CAS号:
分子量:
210.66
Beilstein:
3631658
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
NACRES:
NA.26

生物源

non-animal source

品質等級

化驗

≥98.5%

形狀

crystalline powder

技術

cell culture | mammalian: suitable

雜質

endotoxin, heavy metals, residual solvents, tested

溶解度

H2O: 100 mg/mL

密度

1.42 g/cm3 at 20 °C

負離子痕跡

chloride (Cl-): 16.58-17.00%
sulfate (SO42-): ≤0.020%

正離子痕跡

As: ≤1.0 ppm
NH4+: ≤0.02%
heavy metals: ≤10 ppm

應用

pharmaceutical (small molecule)

異物活動

cytotoxicity, tested

SMILES 字串

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

InChI 密鑰

KWTQSFXGGICVPE-WCCKRBBISA-N

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我们用于生物制药加工的SAFC® 系列优质原料经过严格的质量控制流程,配合记录文件和技术专长帮助我们的客户达到M-Clarity Program规定的要求。

M-Clarity Program

我们全面的上游工艺化学品系列不仅为生物制药生产商提供生产传统和创新治疗药物所需的优质原料,而且帮助他们更快地将产品投放市场并简化监管问题。请相信我们能够为您带来透明供应链的和可靠的全球采购能力,以最佳的法规支持和服务简化您的产品认证。

應用

L-精氨酸是一种非必需氨基酸。 它被作为细胞培养基成分用于治疗性重组蛋白和单克隆抗体的商业化生物制造。L-精氨酸单盐酸盐是一种改良型L-精氨酸,具有更好的溶解度。

生化/生理作用

一氧化氮合成酶的底物,可以转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。

法律資訊

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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