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品質等級
化驗
≥97% (HPLC)
形狀
powder
儲存條件
protect from light
顏色
gray-brown
溶解度
DMSO: >10 mg/mL
儲存溫度
2-8°C
SMILES 字串
O=C1CC2=C(NC3=C2C=C(Br)C=C3)C4=C(C=CC=N4)N1
InChI
1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20)
InChI 密鑰
NTSBZVCEIVPKBJ-UHFFFAOYSA-N
生化/生理作用
1-Azakenpaullone 是一种细胞渗透性、有效的选择性糖原合酶激酶 3 抑制剂3β (GSK3β)与 CDK 的交叉反应性低 100 倍。1-Azakenpaullone 可与 BIO 和 CHIR99021 一起用作 GSK3 抑制的“金标准”。
1-氮杂坎帕罗酮(AZP)可刺激β-连环蛋白相关基因的转录。该化合物能诱导β细胞的增殖和复制。
注意
空气敏感
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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