推荐产品
生物源
goat
品質等級
重組細胞
expressed in goat
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
lyophilized powder
物種活性
human
技術
immunohistochemistry: 5-15 μg/mL using cells and tissues
indirect ELISA: 0.5-1.0 μg/mL
western blot: 0.1-0.2 μg/mL
UniProt登錄號
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... ANGPT1(284)
一般說明
Angiopoietin 1 is an endothelial cell-specific protein that is a ligand for the TIE2 tyrosine receptor. Angiopoietin 1 is critical for mature blood vessel formation.
Angiopoietin-1 (ANG-1) activates Tie-2 signaling in endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth, and stabilization,. ANG-1 is closely related to ANG-2. Both ANG-1 and ANG-2, with their receptor Tie-2, regulate embryonic vasculogenesis and angiogenisis, adult angiogenic sprouting, as well as endothelial cell proliferation.
免疫原
purified, NSO-derived, recombinant human ANG-1.
應用
Goat anti-angiopoietin-1 can be used for immunohistochemistry (5-15 μg/mL), indirect ELISA (0.5-1.0 μg/mL) and western blot (0.1-0.2 μg/mL).
外觀
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
N Jones et al.
Nature reviews. Molecular cell biology, 2(4), 257-267 (2001-04-03)
Angiogenesis is required for normal embryonic vascular development and aberrant angiogenesis contributes to several diseases, including cancer, diabetes and tissue ischaemia. What are the molecular mechanisms that regulate this important process? The Tie family of receptors and their ligands, the
L M Orre et al.
Oncogene, 32(49), 5531-5540 (2013-06-12)
S100A4 is a small calcium-binding protein that is commonly overexpressed in a range of different tumor types, and it is widely accepted that S100A4 has an important role in the process of cancer metastasis. In vitro binding assays has shown
P C Maisonpierre et al.
Science (New York, N.Y.), 277(5322), 55-60 (1997-07-04)
Angiogenesis is thought to depend on a precise balance of positive and negative regulation. Angiopoietin-1 (Ang1) is an angiogenic factor that signals through the endothelial cell-specific Tie2 receptor tyrosine kinase. Like vascular endothelial growth factor, Ang1 is essential for normal
B Witzenbichler et al.
The Journal of biological chemistry, 273(29), 18514-18521 (1998-07-11)
Angiopoietin-1 and its putative natural antagonist, angiopoietin-2, were recently isolated, and the critical role of angiopoietin-1 in embryogenic angiogenesis was demonstrated by targeted gene disruption. Specific biological effects of angiopoietin-1, however, have yet to be defined. In this study we
Natalie R Leach et al.
Virology, 406(1), 127-137 (2010-08-03)
The nuclear lamina is thought to be a steric barrier to the herpesvirus capsid. Disruption of the lamina accompanied by phosphorylation of lamina proteins is a conserved feature of herpesvirus infection. In HSV-1-infected cells, protein kinase C (PKC) alpha and
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