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Merck
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Key Documents

62966

Sigma-Aldrich

L-α-Lysophosphatidylinositol sodium salt from soybean

≥98.0% (TLC)

别名:

1-Acyl-sn-glycero-3-phospho-(1-D-myo-inositol)

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About This Item

MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

生物源

soybean

品質等級

化驗

≥98.0% (TLC)

形狀

powder

雜質

primarily palmitic acid
stearic acid

官能基

phospholipid

脂質類型

phosphoglycerides

運輸包裝

ambient

儲存溫度

−20°C

生化/生理作用

Lysophosphatidylinositol, an endogenous phospholipid, is a novel ligand for the orphan G protein-coupled receptor 55 (GPR55) . Lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT (nuclear factor of activated T cells) activation in human embryonic kidney 293 cells .

準備報告

by phospholipase A2-treatment of 3-sn-phosphatidylinositol

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Christopher M Henstridge et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(1), 183-193 (2008-09-02)
The endogenous phospholipid l-alpha-lysophosphatidylinositol (LPI) was recently identified as a novel ligand for the orphan G protein-coupled receptor 55 (GPR55). In this study we define the downstream signaling pathways activated by LPI in a human embryonic kidney (HEK) 293 cell
Saori Oka et al.
Biochemical and biophysical research communications, 362(4), 928-934 (2007-09-04)
GPR55 is an orphan G protein-coupled receptor. In this study, we explored a possible endogenous ligand for GPR55 using HEK293 cells which expressed GPR55. We found that lysophosphatidylinositol induced rapid phosphorylation of the extracellular signal-regulated kinase in transiently or stably

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