50239

甘氨酸

≥99.0% (NT), suitable for ligand binding assays, BioUltra

• 别名: 三甘氨酸, 甘氨酰-甘氨酰-甘氨酸
• 线性分子式: NH₂CH₂CONHCH₂CONHCH₂COOH
• CAS号: 556-33-2
• 分子量: 189.17
• Beilstein: 1711130
• EC號碼: 209-122-0
• MDL號碼: MFCD00036223
• 分類程式碼代碼: 12352209
• PubChem物質ID: 57651245
• NACRES: NA.26

属性

• product name: 甘氨酸, BioUltra, ≥99.0% (NT)
• 產品線: BioUltra
• 品質等級: 100
• 化驗: ≥99.0% (NT)
• 形狀: powder
• 技術: ligand binding assay: suitable
• 雜質: insoluble matter, passes filter test
• 燃燒殘留物: ≤0.1% (as SO₄)
• 損耗: ≤0.5% loss on drying, 110 °C
• 顏色: white
• pH值: 4.5-6.0 (25 °C, 0.5 M in H₂O)
• 溶解度: H₂O: 0.5 M at 20 °C, clear, colorless
• 負離子痕跡: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• 正離子痕跡: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤50 mg/kg; Bi: ≤5 mg/kg; Ca: ≤20 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• &lambda ；: 0.5 M in H₂O
• 紫外吸收: λ: 260 nm A_max: 0.15; λ: 280 nm A_max: 0.10
• SMILES 字串: NCC(=O)NCC(=O)NCC(O)=O
• InChI: 1S/C6H11N3O4/c7-1-4(10)8-2-5(11)9-3-6(12)13/h1-3,7H2,(H,8,10)(H,9,11)(H,12,13)
• InChI 密鑰: XKUKSGPZAADMRA-UHFFFAOYSA-N

说明

Amino Acid Sequence

Gly-Gly-Gly

一般說明

甘氨酸-甘氨酸-甘氨酸或三甘氨酸是一种由三个甘氨酸残基组成的柔性多肽接头，由肽键按线性顺序连接而成。甘氨酸接头连接单一蛋白的多个结构域，而不影响每个结构域的功能。

應用

<ul>
<li><strong>Targeting PEPT1: a novel strategy to improve the antitumor efficacy of doxorubicin in human hepatocellular carcinoma therapy:</strong> Research explores Gly-Gly-Gly peptides as potential enhancers for drug transport efficiency, positioning them as valuable tools in clinical diagnostic peptide development for targeted cancer therapies (Gong et al., 2017).</li>
<li><strong>Iminopyridine complexes of manganese, rhenium, and molybdenum derived from amino ester methylserine and peptides Gly-Gly, Gly-Val, and Gly-Gly-Gly: self-assembly of the peptide chains:</strong> This study demonstrates the use of Gly-Gly-Gly in the synthesis of complex metal-peptide frameworks for potential use in high-purity peptide applications in IVD manufacturing (&Aacute;lvarez et al., 2012).</li>
</ul>

生化／生理作用

用于通过缩二脲反应重现血清蛋白测量和测定氨基三肽酶的底物。

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)