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48760

Sigma-Aldrich

庆大霉素 硫酸酯 来源于紫红小单孢菌

≥590 μg/mg of gentamicin

别名:

Gentamicin C1

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About This Item

线性分子式:
C19-21H39-43N5O7 · 2.5H2SO4
CAS号:
1405-41-0
EC號碼:
215-778-9
MDL號碼:
MFCD00270181
分類程式碼代碼:
51281651
eCl@ss:
42020823
PubChem物質ID:
329757401
NACRES:
NA.76

生物源

Micromonospora purpurea

品質等級

200

形狀

powder

光學活性

[α]/D 107.0 to 121.0°, c = 10% in H2O

比活性

≥590 μg/mg of gentamicin

分子量

Mr 694-723

損耗

≤18.0% loss on drying

顏色

white to off-white

pH值

3.5-5.5 (4% in H2O)

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria
mycoplasma

作用方式

protein synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6O[C@@H](CC[C@H]6N)[C@@H](C)N)[C@@H]5O.CN[C@H](C)[C@@H]7CC[C@@H](N)[C@H](O7)O[C@@H]8[C@@H](N)C[C@@H](N)[C@H](O[C@H]9OC[C@](C)(O)[C@H](NC)[C@H]9O)[C@H]8O

InChI

1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1

InChI 密鑰

RDEIXVOBVLKYNT-HDZPSJEVSA-N

一般說明

Chemical structure: aminoglycoside

應用

Used as a selection agent (gentamicin-resistance gene) in molecular biology applications. It inhibits the growth of a wide variety of grampositive and gram-negative microorganisms including strains resistant to tetracycline, chloramphenicol, kanamycin and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus and Streptococcus.

生化／生理作用

作用方式：通过结合到 50S 核糖体亚基的 L6 蛋白上抑制蛋白质的合成。
抗菌谱：革兰氏阴性菌、革兰氏阳性菌和支原体。

包裝

1g, 5g, 25g

單位定義

1U 对应于 1μg USP 级硫酸庆大霉素标准品

準備報告

Freely soluble in water, practically insoluble in alcohol and ether.

其他說明

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H317

危險分類

Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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