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Merck

17927

Sigma-Aldrich

9-氧代-10 (9 H )-吖啶乙酸

for HPLC derivatization, ≥99.0% (T)

别名:

10-(羧甲基)-9 (10H) 吖啶酮, (9,10-二氢-9-氧代-10-吖啶基)乙酸

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About This Item

经验公式(希尔记法):
C15H11NO3
CAS号:
分子量:
253.25
Beilstein:
227508
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.32

等級

for HPLC derivatization

品質等級

化驗

≥99.0% (T)

形狀

solid

mp

~289 °C (dec.)

SMILES 字串

OC(=O)CN1c2ccccc2C(=O)c3ccccc13

InChI

1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)

InChI 密鑰

UOMKBIIXHQIERR-UHFFFAOYSA-N

應用

9-氧-10 (9H)-吖啶乙酸及其类似物被用于研究其作为干扰素诱导剂的潜在活性。

其他說明

HPLC 中荧光测定用氨基酸柱前衍生化试剂;药剂学基础

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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V M Frolov et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 57(5-6), 18-27 (2012-11-20)
The use of reamberin and cycloferon combination for increasing the antibacterial therapy efficacy in patients with chronic sepsis (CS) was studied. It was shown that the combination provided more rapid elimination of the CS exacerbation symptoms, normalization of the hematologic
Tolerance or hyperreactivity to interferon induction by sodium salt of 9-oxo-10-acridineacetic acid and analogs in mice and in the mouse macrophage cultures.
Szulc B, Inglot AD, Inglot O.
Arch. Immunol. Ther. Exp., 35, 389-395 (1987)
Competition of sodium salt of 9-oxo-10-acridineacetic acid with analogs during induction of interferon in the mouse bone marrow-derived macrophages.
Szulc B, Inglot AD, Szulc Z, Mlochowski J.
Arch. Immunol. Ther. Exp., 33, 287-297 (1985)
S.A. Lyakhov et al.
Pharmazie, 49, 367-367 (1994)
E D Bazhanova
Eksperimental'naia i klinicheskaia farmakologiia, 75(10), 42-46 (2012-12-18)
A detailed analysis of the literature data gives contradictory information about the role of interferon-alpha in the regulation of apoptosis, while there are almost no data on the participation of cycloferon in this process. Results of original experiments in recent

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