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Merck

Y0001406

氨基葡萄糖 盐酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

D- (+)-氨基葡萄糖 盐酸盐, 2-氨基-2-脱氧-D-葡萄糖 盐酸盐, 壳糖胺 盐酸盐

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About This Item

经验公式(希尔记法):
C6H13NO5 · HCl
CAS号:
分子量:
215.63
Beilstein:
4157370
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

agency

EP Reference Standard

API 家族

glucosamine

製造商/商標名

EDQM

mp

190-194 °C (dec.) (lit.)

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1

InChI 密鑰

QKPLRMLTKYXDST-NSEZLWDYSA-N

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一般說明

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

應用

盐酸氨基葡萄糖EP参考标准品的预期用途是欧洲药典规定的实验室测试。

生化/生理作用

葡萄糖胺是一种氨基糖,是己糖胺生物合成途径的前体,可导致形成UDP-N-乙酰葡糖胺(UDP-GlcNAc),然后将其用于制备糖胺聚糖、蛋白多糖和糖脂。 D-(+)-葡萄糖胺抑制念珠菌酵母菌株与细菌菌株唾液链球菌的共聚集。

包裝

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他說明

可能适用相应的销售限制。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Oshra Betzer et al.
ACS nano, 8(9), 9274-9285 (2014-08-19)
A critical problem in the development and implementation of stem cell-based therapy is the lack of reliable, noninvasive means to image and trace the cells post-transplantation and evaluate their biodistribution, final fate, and functionality. In this study, we developed a
Ji-Sun Hwang et al.
Metabolism: clinical and experimental, 64(3), 368-379 (2014-12-18)
This study investigated the potential of glucosamine (GlcN) to affect body weight gain and insulin sensitivity in mice normal and at risk for developing diabetes. Male C57BL/6J mice were fed either chow diet (CD) or a high fat diet (HFD)
Khadijeh Jamialahmadi et al.
Environmental toxicology and pharmacology, 38(1), 212-219 (2014-06-25)
Glucosamine (GlcN) is an important precursor in the biochemical synthesis of glycosylated proteins and lipids in human body. It gains importance because of its contribution to human health and its multiple biological and therapeutic effects. In this study, the in
Viktor Chesnokov et al.
Cancer cell international, 14, 45-45 (2014-06-17)
We have reported that the glucosamine suppressed the proliferation of the human prostate carcinoma cell line DU145 through inhibition of STAT3 signaling. DU145 cells autonomously express IL-6 and the IL-6/STAT3 signaling is activated. IL-6 receptor subunits are subject to N-glycosylation
Hiba Al-Hamidi et al.
Pharmaceutical development and technology, 20(1), 74-83 (2014-01-08)
The solid dispersion technique is one of the most effective methods for improving the dissolution rate of poorly water-soluble drugs; however this is reliant on a suitable carrier and solvent being selected. The work presented explores amino sugars (d-glucosamine HCl

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