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Merck

A8625

Sigma-Aldrich

N -乙酰基- D -氨基葡萄糖

≥99% (HPLC)

别名:

2-乙酰氨基-2-脱氧-D-葡萄糖, D-GlcNAc

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About This Item

经验公式(希尔记法):
C8H15NO6
CAS号:
分子量:
221.21
Beilstein:
1727589
EC號碼:
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

生物源

crab (red)

品質等級

化驗

≥99% (HPLC)

形狀

powder

技術

HPLC: suitable

顏色

white to off-white

mp

211 °C (dec.) (lit.)

溶解度

H2O: 50 mg/mL, clear to very slightly hazy (colorless to faint yellow solution)

儲存溫度

−20°C

SMILES 字串

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1

InChI 密鑰

OVRNDRQMDRJTHS-RTRLPJTCSA-N

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一般說明

N-乙酰葡糖胺(GlcNAc)是葡糖胺(GlcN)的乙酰化衍生物。它是蛋白聚糖、糖蛋白、糖胺聚糖(GAG)和结缔组织中的其他合成单体的重要成分。

應用

N-乙酰-D-葡萄糖胺已用于:
  • 用作凝集素组织化学竞争性抑制糖
  • 用作培养伯氏疏螺旋体螺旋体菌(Borrelia burgdorferi spirochetes)株的 Barbour-Stonner-Kelly (BSK) 培养基成分
  • 用作重悬肺炎链球菌(Streptococcus pneumoniae)菌株的结合缓冲液成分,以便通过抑制测定检验M-ficolin纤维胶凝蛋白与肺炎链球菌(S. pneumoniae )菌株结合的特异性

生化/生理作用

N-乙酰葡糖胺(GlcNAc)主要用于食品、化妆品和制药行业。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Lucy G Weaver et al.
Carbohydrate research, 371, 68-76 (2013-03-26)
Poly-N-acetylglucosamine (PNAG) saccharides are an important constituent of bacterial biofilms, such as those produced by Staphylococcus aureus. We have developed a simple two-step iterative method for the synthesis of β-(1→6)-glucosamine oligosaccharides that are structurally similar to PNAG. We illustrate the
Bingwu Yu et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 228, 159-165 (2013-01-09)
Strong (1)H-(1)H coupling can significantly reduce the accuracy of (1)J(CH) measured from frequency differences in coupled HSQC spectra. Although accurate (1)J(CH) values can be extracted from spectral simulation, it would be more convenient if the same accurate (1)J(CH) values can
Yasuhito Onodera et al.
The Journal of clinical investigation, 124(1), 367-384 (2013-12-10)
There is a considerable resurgence of interest in the role of aerobic glycolysis in cancer; however, increased glycolysis is frequently viewed as a consequence of oncogenic events that drive malignant cell growth and survival. Here we provide evidence that increased
Colette Cywes-Bentley et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(24), E2209-E2218 (2013-05-30)
Microbial capsular antigens are effective vaccines but are chemically and immunologically diverse, resulting in a major barrier to their use against multiple pathogens. A β-(1→6)-linked poly-N-acetyl-d-glucosamine (PNAG) surface capsule is synthesized by four proteins encoded in genetic loci designated intercellular
Mikkel Girke Jørgensen et al.
Genes & development, 27(10), 1132-1145 (2013-05-15)
Many bacterial small RNAs (sRNAs) regulate gene expression through base-pairing with mRNAs, and it has been assumed that these sRNAs act solely by this one mechanism. Here we report that the multicellular adhesive (McaS) sRNA of Escherichia coli uniquely acts

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