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Merck
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文件

SMB01383

Sigma-Aldrich

PhIP

≥95% (HPLC)

别名:

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

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About This Item

经验公式（希尔记法）:
C13H12N4
CAS号:
105650-23-5
分子量:
224.26
MDL號碼:
MFCD00210745
分類程式碼代碼:
12352100
NACRES:
NA.28

生物源

synthetic

品質等級

200

化驗

≥95% (HPLC)

形狀

solid

運輸包裝

2-8°C

儲存溫度

2-8°C

SMILES 字串

NC1=NC2=NC=C(C3=CC=CC=C3)C=C2N1C

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一般說明

PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) is a dietary genotoxic carcinogen formed in heat processed meat and fish via the Maillard reaction. PhIP is a primary metabolite activated by CYP1A2 and N-acetyltransferase 1 or sulfotransferase to DNA reactive metabolite.

生化／生理作用

Carcinogen developed in grilled meats. Induces breast and colon cancer in rats.

象形圖

Skull and crossbonesHealth hazard
GHS06,GHS08

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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