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Merck

PHR1701

Supelco

醋酸曲安奈德

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

醋酸曲安奈德, 9α-氟-11β,16α,17α,21-四羟基-1,4-孕甾二烯-3,20-二酮-16,17-丙酮化合物, 9α-氟-16α-羟基波尼松龙 16α,17α-丙酮化合物

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About This Item

经验公式(希尔记法):
C24H31FO6
CAS号:
分子量:
434.50
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to Ph. Eur. T1900000
traceable to USP 1677002

API 家族

triamcinolone

CofA

current certificate can be downloaded

包裝

pkg of 1 g

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

InChI 密鑰

YNDXUCZADRHECN-JNQJZLCISA-N

基因資訊

human ... NR3C1(2908)

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一般說明

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Triamcinolone Acetonide is a glucocorticoid and a derivative of pregnane, used mainly in the treatment of rheumatic disease, allergic and dermatologic symptoms.

應用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Triamcinolone Acetonide may be used as a pharmaceutical standard for the determination of the analyte in drug dosage forms by high performance liquid chromatography and spectrophotometry.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC2813 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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Triamcinolone acetonide.
Jeal W and Faulds D
Drugs, 53(2), 257-280 (1997)
Determination of methylparaben, propylparaben, triamcinolone acetonide and its degradation product in a topical cream by RP-HPLC.
Matysova L, et al.
Analytical and Bioanalytical Chemistry, 376(4), 440-443 (2003)
Simultaneous determination of terbinafine HCL and triamcinolone acetonide by UV derivative spectrophotometry and spectrodensitometry.
El-Saharty YS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 28(3-4), 569-580 (2002)
Simultaneous determination of triamcinolone acetonide and oxymetazoline hydrochloride in nasal spray formulations by HPLC.
Sudsakorn S, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(5), 1273-1280 (2006)

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