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等級
certified reference material
pharmaceutical secondary standard
品質等級
agency
traceable to Ph. Eur. Y0001562
traceable to USP 1227006
API 家族
doxylamine
CofA
current certificate can be downloaded
技術
HPLC: suitable
gas chromatography (GC): suitable
應用
pharmaceutical (small molecule)
格式
neat
儲存溫度
2-30°C
SMILES 字串
OC(=O)CCC(O)=O.CN(C)CCOC(C)(c1ccccc1)c2ccccn2
InChI
1S/C17H22N2O.C4H6O4/c1-17(20-14-13-19(2)3,15-9-5-4-6-10-15)16-11-7-8-12-18-16;5-3(6)1-2-4(7)8/h4-12H,13-14H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
InChI 密鑰
KBAUFVUYFNWQFM-UHFFFAOYSA-N
基因資訊
human ... HRH1(3269)
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一般說明
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Doxylamine succinate is an antihistaminic drug generally employed for the prevention of morning sickness in pregnant women.
Doxylamine succinate is an antihistaminic drug generally employed for the prevention of morning sickness in pregnant women.
應用
Doxylamine Succinate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析報告
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他說明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
腳註
To see an example of a Certificate of Analysis for this material enter LRAC3445 in the slot below. This is an example certificate only and may not be the lot that you receive.
訊號詞
Warning
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
Development and Validation of a Rapid Chemometrics Assisted RP-HPLC with PDA Detection Method for the Simultaneous Estimation of Pyridoxine HCl and Doxylamine Succinate in Bulk and Pharmaceutical Dosage Form
Chromatography Research International, 2014(2), 91-97 (2014)
Formulation and evaluation of orodispersible tablet of taste masked doxylamine succinate using ion exchange resin
Journal of King Saud University - Science, 22(4), 229-240 (2010)
Liquid chromatographic determination of amines in complex cough-cold formulations
International Journal of Pharmaceutics, 53(2), 91-97 (1989)
Analysis of pharmaceutical preparations containing antihistamine drugs by micellar liquid chromatography
Journal of Pharmaceutical and Biomedical Analysis, 40(2), 312-321 (2006)
Electrophoresis, 28(11), 1779-1787 (2007-04-24)
An MEKC method was developed in order to separate a cold medicine formulation containing acetaminophen, ephedrine sulfate, doxylamine succinate, and dextromethorphan hydrobromide as active pharmaceutical ingredients. Because of their similar physical and chemical properties, it was a challenge to separate
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