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Supelco

Super-DHB

suitable for matrix substance for MALDI-MS, ≥99.0%

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About This Item

CAS号:
分類程式碼代碼:
12000000
NACRES:
NA.21

品質等級

化驗

≥99.0% (sum of DHB and 2-hydroxy-5-methoxybenzoic acid, HPLC)
≥99.0%

分析物功能類別

polymers

分析物化學類別

glycans, peptides, proteins

技術

MALDI-MS: suitable

溶解度

methanol: 1%, clear

正離子痕跡

Ca: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤5 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

適合性

suitable for matrix substance for MALDI-MS

一般說明

“super-DHB”基质由2,5-DHB和2-羟基-5-甲氧基苯甲酸的混合物[9:1(w / w)]组成,该混合比例经验证为最有效的。2-羟基-5-甲氧基苯甲酸添加剂的有益效果归因于无序的2,5-DHB晶格,从而导致离子解吸增强(即“更软”解吸)和内部能量降低,这反过来导致亚稳碎裂的减少。据报道,对于标准葡聚糖混合物来说,其灵敏度可增加高达2至3倍,并伴随着增强的分辨率,其原因是亚稳离子形成的减少。另有报道表明,super-DHB基质可在胰蛋白酶糖肽中产生增强的信号。使用super-DHB基质可减少基质背景离子的存在,并导致聚糖信号在质谱中表现出更好的信噪比和更高的分辨率。

應用


  • Glycan and Protein Analysis of Glycoengineered Bacterial E. coli Vaccines by MALDI-in-Source Decay FT-ICR Mass Spectrometry: This study demonstrates the application of Super-DHB as a matrix in advanced mass spectrometry for the detailed characterization of glycoengineered vaccines, essential for researchers in pharmaceuticals and life science manufacturing (Nicolardi et al., 2022).

  • An Improved Method for Rapid Detection of Mycobacterium abscessus Complex Based on Species-Specific Lipid Fingerprint by Routine MALDI-TOF: Highlights the use of Super-DHB in enhancing the lipid fingerprinting capabilities of MALDI-TOF mass spectrometry, critical for rapid microbial identification in medical microbiology and pharmaceutical research (Jia Khor et al., 2021).

  • Discrimination of bovine milk from non-dairy milk by lipids fingerprinting using routine matrix-assisted laser desorption ionization mass spectrometry: Illustrates the role of Super-DHB in differentiating dairy and non-dairy milks based on lipid profiles using MALDI-MS, vital for food scientists and chemists in quality control and food safety (England et al., 2020).

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

分析報告

DHB和2-羟基-5-甲氧基苯甲酸的混合物(9:1)

相關產品

产品编号
说明
价格

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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