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Merck

39319

Supelco

2,5-二羟基苯甲酸

matrix substance for MALDI-MS, ≥99.5% (HPLC), Ultra pure

别名:

2,5-DHBA, DHB, 氢醌羧酸, 龙胆酸

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About This Item

线性分子式:
(HO)2C6H3CO2H
CAS号:
分子量:
154.12
Beilstein:
2209119
EC號碼:
MDL號碼:
分類程式碼代碼:
41116105
PubChem物質ID:
NACRES:
NA.21

等級

matrix substance for MALDI-MS

品質等級

化驗

≥99.5% (HPLC)

分析物功能類別

polymers

分析物化學類別

glycans, lipids, organic molecules, peptides, proteins

技術

MALDI-MS: suitable

mp

203-207 °C
204-208 °C (lit.)

溶解度

methanol: 10 mg/mL, clear

正離子痕跡

Al: ≤1 mg/kg
Ba: ≤1 mg/kg
Ca: ≤1 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤1 mg/kg
Li: ≤1 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Na: ≤1 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

SMILES 字串

OC(=O)c1cc(O)ccc1O

InChI

1S/C7H6O4/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,8-9H,(H,10,11)

InChI 密鑰

WXTMDXOMEHJXQO-UHFFFAOYSA-N

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應用


  • Quantitative MALDI-MS and Imaging of Fungicide Pyrimethanil in Strawberries with 2-Nitrophloroglucinol as an Effective Matrix.: This research highlights the application of 2,5-Dihydroxybenzoic acid (DHB) as an effective matrix for MALDI-MS imaging, providing enhanced detection sensitivity for fungicides in agricultural samples. The study showcases DHB′s role in improving the quantification and spatial resolution of pesticide residues within fruit matrices, demonstrating its utility in food safety and chemical analysis (Liang et al., 2024).

  • A maize enzyme from the 2-oxoglutarate-dependent oxygenase family with unique kinetic properties, mediates resistance against pathogens and regulates senescence.: Utilizing 2,5-Dihydroxybenzoic acid in enzyme kinetics studies, this paper reveals its critical role in modulating plant defense mechanisms against pathogens. The study provides insights into the biochemical pathways influenced by DHB, underscoring its importance in plant biochemistry and resistance breeding (Casati et al., 2024).

  • Unveiling the distribution of free and bound phenolic acids, flavonoids, anthocyanins, and proanthocyanidins in pigmented and non-pigmented rice genotypes.: This comprehensive analysis employs 2,5-Dihydroxybenzoic acid to investigate the phenolic content in different rice varieties, highlighting its role in enhancing the detection of health-beneficial compounds. The research supports DHB′s application in nutritional studies and crop quality assessments (Thulasinathan et al., 2024).

  • Novel Small Molecule Matrix Screening for Simultaneous MALDI Mass Spectrometry Imaging of Multiple Lipids and Phytohormones.: Leveraging the chemical properties of 2,5-Dihydroxybenzoic acid, this study introduces a novel matrix for MALDI-MS imaging, enhancing the simultaneous visualization of lipids and phytohormones in biological tissues. It highlights the versatility of DHB in facilitating complex biochemical analyses (Shi et al., 2024).

  • 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine as a Novel Matrix for Enhanced MALDI Imaging of Tissue Metabolites.: This research demonstrates the use of DHB-based matrices to improve the MALDI imaging of metabolites, offering greater sensitivity and specificity in clinical diagnostics and metabolic studies. The findings contribute to the broader application of DHB in analytical chemistry (Wang et al., 2024).

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

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产品编号
说明
价格

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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V. K. Ahluwalia
Intermediates for Organic Synthesis, 78-79 (2005)
Ya-Shiuan Lin et al.
Analytical chemistry, 74(22), 5793-5798 (2002-12-05)
This work presents a novel method for direct desorption/ ionization of analytes from sol-gel-derived film. 2,5-Dihydroxy benzoic acid (DHB), a common MALDI matrix, was incorporated into a sol-gel polymeric structure. The sol-gel-derived DHB thin film can assist the mass analysis
Mandana Hunter et al.
Journal of neurochemistry, 146(5), 613-630 (2018-05-29)
The human subventricular zone (SVZ) has a defined cytological and neurochemical architecture, with four constituent laminae that act in concert to support its neurogenic activity. Lipidomic specialisation has previously been demonstrated in the neurologically normal human SVZ, with enrichment of
B E Cham et al.
Clinical chemistry, 26(1), 111-114 (1980-01-01)
We have developed a specific and sensitive method for the determination of salicylic acid, salicyluric acid, and gentisic acid in urine. Any proteins present are precipitated with methyl cyanide. After centrifugation, an aliquot of the supernate is directly injected into
F Bochner et al.
Clinical pharmacology and therapeutics, 30(2), 266-275 (1981-08-01)
Single oral doses of aspirin (ASA, 1,500 mg), sodium salicylate (NaSA, 1,500 mg, 1,200 mg), and salicyluric acid (SUA, 500 mg) were given to five subjects. Serial plasma and urine samples were collected for 24 hr (plasma) and up to

商品

One of the most important aspects of our ultra-pure MALDI matrix substances is their ability to dissolve rapidly and completely; a brief vortex mixing is typically sufficient.

One of the most important aspects of our ultra-pure MALDI matrix substances is their ability to dissolve rapidly and completely; a brief vortex mixing is typically sufficient.

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