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Merck

46429

Supelco

甲巯咪唑

VETRANAL®, analytical standard

别名:

1-甲基-2-咪唑硫醇, 2-巯基-1-甲基咪唑

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About This Item

经验公式(希尔记法):
C4H6N2S
CAS号:
分子量:
114.17
Beilstein:
108646
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

產品線

VETRANAL®

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

144-147 °C (lit.)

應用

cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

形式

neat

SMILES 字串

CN1C=CNC1=S

InChI

1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)

InChI 密鑰

PMRYVIKBURPHAH-UHFFFAOYSA-N

基因資訊

human ... TPO(7173)

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一般說明

甲硫咪唑是一种甲状腺激素抑制剂和一种抗激素药,广泛用于甲亢治疗药物。

應用

有关合适的仪器技术的更多信息,请参阅产品的分析证书。想要获得更多支持,请联系技术服务部。
甲巯咪唑可作为混合模式固相萃取-反相高效液相色谱-紫外检测法(MMSPE-RP-HPLC-UV)测定鱼匀浆中分析物的参考标准品。

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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MMSPE-RP-HPLC method for the simultaneous determination of methimazole and selected metabolites in fish homogenates.
Hollosi L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 921-924 (2004)
Yi Wang et al.
Toxicology and applied pharmacology, 271(2), 257-265 (2013-05-28)
Neurotoxicity of iodine deficiency-induced hypothyroidism during developmental period results in serious impairments of brain function, such as learning and memory. These impairments are largely irreversible, and the underlying mechanisms remain unclear. In addition to hypothyroidism, iodine deficiency may cause hypothyroxinemia
Coralie Leblicq et al.
Pediatrics, 131(2), e616-e619 (2013-01-09)
A 15-year-old girl presented with chorea as a first sign of Graves' hyperthyroidism. Chorea abated with antithyroid drug treatment and reappeared when hyperthyroidism recurred but not when thyrotropin receptor antibodies increased after administration of (131)I. Therefore, chorea in this patient
Mal-Soon Shin et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 31(3), 214-223 (2013-01-19)
Thyroid hormones play a crucial role in new neuron production and maturation during brain development. Physical exercise is known to promote cell survival and functional recovery after brain injuries. In the present study, we investigated the effects of treadmill exercise
F S Boretti et al.
Journal of veterinary internal medicine, 27(2), 377-381 (2013-02-13)
Transdermal methimazole is an acceptable alternative to oral treatment for hyperthyroid cats. There are, however, no studies evaluating the duration of T4 suppression after transdermal methimazole application. Such information would be valuable for therapeutic monitoring. To assess variation in serum

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