26454

硬脂酸镁

puriss., meets analytical specification of Ph. Eur., BP, ≥90% stearic and palmitic acid basis, ≥40% stearic acid basis (GC), 4.0-5.0% Mg basis (calc on dry sub.)

• 别名: 十八酸 镁盐
• 线性分子式: [CH₃(CH₂)₁₆CO₂]₂Mg
• CAS号: 557-04-0
• 分子量: 591.24
• Beilstein: 3919702
• EC號碼: 209-150-3
• MDL號碼: MFCD00036391
• 分類程式碼代碼: 12352106
• PubChem物質ID: 57648176
• NACRES: NA.22

属性

• 等級: puriss.
• 化驗: ≥40% stearic acid basis (GC); ≥90% stearic and palmitic acid basis; 4.0-5.0% Mg basis (calc on dry sub.)
• 品質: meets analytical specification of Ph. Eur., BP
• 雜質: acidity or alkalinity, complies; microbiological impurity, in accordance; residual solvents, complies
• 損耗: ≤6.0% loss on drying, 105 °C
• mp: 200 °C (lit.)
• 酸價: 195‑210(fatty acid)
• 溶解度: alcohol: insoluble; diethyl ether: insoluble; water: insoluble
• 負離子痕跡: chloride (Cl^-): ≤1000 mg/kg; sulfate (SO₄^2-): ≤5000 mg/kg
• 正離子痕跡: Cd: ≤3 mg/kg; Ni: ≤5 mg/kg; Pb: ≤10 mg/kg
• 適合性: in accordance for fatty acid composition; passes test for identity
• 應用: pharmaceutical (small molecule)
• SMILES 字串: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
• InChI 密鑰: HQKMJHAJHXVSDF-UHFFFAOYSA-L

说明

應用

硬脂酸镁已被用作片剂和胶囊润滑剂。也用于制备微囊。

生化／生理作用

硬脂酸镁是硬脂酸的镁盐，具有润滑性能，因此在将化学粉末压制成固体片剂时可防止成分粘在制造设备上。用硬脂酸镁干包衣可改善流动性、改善流动性和润滑效果、可压片性以及不受抑制的溶出度。

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves