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等級
technical grade
形狀
powder
成份
palmitate salt, 25%
stearate salt, 65%
mp
200 °C (lit.)
SMILES 字串
CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
InChI
1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
InChI 密鑰
HQKMJHAJHXVSDF-UHFFFAOYSA-L
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一般說明
硬脂酸镁（Mg-St）是硬脂酸的镁盐。已制备其脱水、二水和三水合物形式。已有研究描述了硬脂酸镁和乳糖颗粒混合片剂的制备。研究了混合时间对压缩片剂硬度、崩解时间和挤出力的影响。硬脂酸镁广泛用作制药工业中的润滑剂。它还在延缓溶解过程中发挥作用。已提出通过激光诱导击穿光谱法检测片剂中的硬脂酸镁。
硬脂酸镁，即硬脂酸的盐，在制药片剂中被广泛用作非活性成分。
硬脂酸镁，即硬脂酸的盐，在制药片剂中被广泛用作非活性成分。
應用
硬脂酸镁可用作双氯芬酸钠片剂处方中的辅料。可用于制备盐酸曲马多骨架片。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Jaleh Varshosaz et al.
AAPS PharmSciTech, 7(1), E24-E24 (2006-04-06)
The objective of this work was to develop matrix sustained-release tablets of highly water-soluble tramadol HCl using natural gums (xanthan [X gum] and guar [G gum]) as cost-effective, nontoxic, easily available, and suitable hydrophilic matrix systems compared with the extensively
Effect of mixing time on the lubricating properties of magnesium stearate and the final characteristics of the compressed tablets.
Kikuta J-I and Kitamori N.
Drug Development and Industrial Pharmacy, 20(3), 343-355 (1994)
Louis St-Onge et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 8(2), 272-288 (2005-08-30)
Laser-induced breakdown spectroscopy (LIBS) was evaluated for its potential as a process analytical tool for the rapid determination of magnesium stearate (MgSt) distribution within and between tablets as well as between batches in a typical manufacturing run, and for the
Delay effect of magnesium stearate on tablet dissolution in acidic medium.
Ariyasu A, et al.
International Journal of Pharmaceutics, 511(2), 757-764 (2016)
Paola Bertocchi et al.
Journal of pharmaceutical and biomedical analysis, 37(4), 679-685 (2005-03-31)
The aim of this work was to compare the dissolution behaviour of six diclofenac sodium prolonged release tablets of different brands obtained from the national market. The formulations contain the same amount of drug substance but different types and/or amount
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