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Merck

07270

Sigma-Aldrich

6-氨基己酸甲酯 盐酸盐

≥99.0% (AT)

别名:

Methyl 6-aminocaproate 盐酸盐

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About This Item

线性分子式:
NH2(CH2)5COOCH3 · HCl
CAS号:
分子量:
181.66
Beilstein:
3687692
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥99.0% (AT)

形狀

powder or crystals

反應適用性

reaction type: solution phase peptide synthesis

顏色

white

mp

117-124 °C

應用

peptide synthesis

SMILES 字串

Cl.COC(=O)CCCCCN

InChI

1S/C7H15NO2.ClH/c1-10-7(9)5-3-2-4-6-8;/h2-6,8H2,1H3;1H

InChI 密鑰

YSLDOTFAFZJPOC-UHFFFAOYSA-N

一般說明

Methyl 6-aminohexanoate hydrochloride also known as Methyl 6-aminocaproate hydrochloride, is commonly used in the solution-phase peptide synthesis.

應用

Methyl 6-aminohexanoate hydrochloride is used to synthesize papain-catalyzed peptides.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Papain-catalyzed synthesis of polyglutamate containing a nylon monomer unit
K Yazawa, et.al.
Polymers, 8, 194-194 (2016)
Petr Chytil et al.
Molecular pharmaceutics, 15(9), 3654-3663 (2018-03-16)
Herein, the biodegradable micelle-forming amphiphilic N-(2-hydroxypropyl) methacrylamide (HPMA)-based polymer conjugates with the anticancer drug doxorubicin (Dox) designed for enhanced tumor accumulation were investigated, and the influence of their stability in the bloodstream on biodistribution, namely, tumor uptake, and in vivo
Tomáš Etrych et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 58, 1-12 (2014-03-19)
In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly bound via a pH-sensitive hydrazone and partly via
Martin Studenovský et al.
Anticancer research, 35(2), 753-757 (2015-02-11)
In the present study, we describe the synthesis and physicochemical properties of a novel pH- and thermoresponsive micellar drug delivery system for an anticancer ellipticinium derivative based on the triblock copolymer poly(ethylene oxide)-block-[tert-butylacrylamide-co-6-(N-methacryloylamino)hexanoic acid hydrazide]-block-poly(ethylene oxide). The system was designed

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