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品質等級
化驗
97%
形狀
solid
mp
176-178 °C (lit.)
官能基
amide
chloro
SMILES 字串
CC(=O)Nc1ccc(Cl)cc1
InChI
1S/C8H8ClNO/c1-6(11)10-8-4-2-7(9)3-5-8/h2-5H,1H3,(H,10,11)
InChI 密鑰
GGUOCFNAWIODMF-UHFFFAOYSA-N
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一般說明
4'-氯乙酰苯胺是对乙酰氨基酚中存在的主要杂质，已经通过使用混合模式反相/阳离子交换固定相的新型高效液相色谱法定量。
應用
<ul>
<li><strong>高效液相色谱（HPLC）方法验证：</strong>4-氯乙酰胺被用作硝酸异山梨酯的内部标准品，通过高效液相色谱（HPLC）测定含有硝酸甘油、单硝酸异山梨酯或季戊四醇四硝酸酯的缓释片剂或胶囊中（Gelber and Papas, 1983）。</li>
</ul>
<li><strong>高效液相色谱（HPLC）方法验证：</strong>4-氯乙酰胺被用作硝酸异山梨酯的内部标准品，通过高效液相色谱（HPLC）测定含有硝酸甘油、单硝酸异山梨酯或季戊四醇四硝酸酯的缓释片剂或胶囊中（Gelber and Papas, 1983）。</li>
</ul>
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Tamas A Godany et al.
Chimia, 65(4), 253-255 (2011-06-18)
Lithiation of N-(4-chlorophenyl)-pivalamide (NCP) and two additional substituted acetanilides: 4-fluoroacetanilide (4-F) and 4-chloroacetanilide (4-Cl) has been monitored by means of calorimetry, on-line ATR-IR and UV/vis spectroscopy and endoscopy. The combined on-line monitoring revealed the differences between the reaction paths of
L Koymans et al.
Xenobiotica; the fate of foreign compounds in biological systems, 23(6), 633-648 (1993-06-01)
1. The general mechanism of metabolic oxidation of substrates by cytochromes P450 (P450s) appears to consist of sequential one-electron oxidation steps rather than of a single concerted transfer of activated oxygen species from P450 to substrates. 2. In case of
Octavian Călinescu et al.
Journal of chromatographic science, 50(4), 335-342 (2012-03-13)
Determination of acetaminophen and its main impurities: 4-nitrophenol, 4'-chloroacetanilide, as well as 4-aminophenol and its degradation products, p-benzoquinone and hydroquinone has been developed and validated by a new high-performance liquid chromatography method. Chromatographic separation has been obtained on a Hypersil
Jody A Shoemaker et al.
Journal of AOAC International, 89(1), 201-209 (2006-03-04)
U.S. Environmental Protection Agency (EPA) Method 535 has been developed in order to provide a method for the analysis of "Alachlor ESA and other acetanilide degradation products," which are listed on EPA's 1998 Drinking Water Contaminant Candidate List. Method 535
Anthony F Pizon et al.
Clinical toxicology (Philadelphia, Pa.), 47(2), 132-136 (2008-07-09)
p-Chloroaniline is more potent at producing methemoglobin than aniline in animal models. This case highlights the clinical presentation of an inhalation exposure to p-chloroaniline and associated laboratory analysis. An in-vitro study evaluating the metabolism of p-chloroaniline in human hepatocytes was
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