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Merck
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Key Documents

MATHKSA

Millipore

NEP Control HKSA- PyroMAT® System MAT

Non-endotoxin pyrogen control of heat killed Staphyloccus aureus for use in monocyte activation test

别名:

NEP, NEP control

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About This Item

分類程式碼代碼:
41116130
NACRES:
NA.24

特點

Non-endotoxin pyrogen control of heat killed Staphyloccus aureus for use in monocyte activation test

品質等級

包裝

pkg of 1 vial

製造商/商標名

PyroMAT®

應用

pharmaceutical
pyrogen testing

相容性

configured for PyroDetect System
configured for PyroMAT® System

運輸包裝

ambient

儲存溫度

2-8°C

適合性

pyrogenic bacteria

一般說明

The PyroMAT® System uses cryopreserved Mono-Mac-6 (MM6) human monocytic cells as a source of monocytes. The response to a full range of pyrogens, including endotoxins and non-endotoxin pyrogens (NEPs)is determined by the measurement of interleukin-6 (IL-6) produced by the Mono-Mac-6 cells using ELISA.
NEP control HKSA is a heat-killed preparation of Staphylococcus aureus, supplied in a lyophilized form. HKSA is a non-endotoxin pyrogen (NEP) that activates the TLR2 receptor of monocytes and can be used as a positive control with the PyroMAT® System (Monocyte Activation Test for pyrogen detection).

特異性

TLR-2 agonist

應用

NEP control of heat-killed Staphylococcus aureus can be used as a positive control with the PyroMAT® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

特點和優勢

Endotoxin-free product at concentration of use in MAT

儲存和穩定性

Store unopened vials at 2-8°C
Do not use unopened vials after expiration date
Store resuspended aliquots at -20°C
Shelf life of aliquots can be found on the technical datasheet

法律資訊

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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