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MAB4369

Sigma-Aldrich

Anti-SRF [Serum Response Factor] Antibody, clone 1E1

clone 1E1, from mouse

别名:

serum response factor (c-fos serum response element-binding transcription factor)

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

1E1, monoclonal

物種活性

mouse, human

技術

immunocytochemistry: suitable
western blot: suitable

輸入

sample type neural stem cell(s)
sample type mesenchymal stem cell(s)

同型

IgG1κ

UniProt登錄號

P11831

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ELK3(2004)

一般說明

Serum response factor (SRF) is a nuclear transcription factor that binds to the serum response element (SRE), and is essential for embryonic development of the mesoderm, as well as for the maintenance of adult muscle cells and neurons. As this protein is involved in the downstream regulation of many immediate-early genes, it participates in a variety of cell functions, including cell cycle, apoptosis, cell growth, and cell differentiation. SRF is most commonly activated by serum, LPA, LPS, TPA, growth factors, including TNFalpha, as well as antioxidants and UV light.

特異性

A weak interaction with mouse has also been observed. Reactivity with other species has not been tested.
This monoclonal antibody recognizes SRF.

免疫原

Synthetic human SRF peptide, a.a. 406-508.

應用

Detect SRF [Serum Response Factor] using this Anti-SRF [Serum Response Factor] Antibody, clone 1E1 validated for use in WB & IC.
Immunocytochemistry: Recommended working dilution is 1:500.
Research Category
Stem Cell Research
Research Sub Category
Mesenchymal Stem Cells

Neural Stem Cells

品質

(Based upon representative data from a previous lot).

Western Blotting: Recommended working dilution is 0.5 µg/mL.

標靶描述

~52 kDa

外觀

Protein G Purified
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide.

儲存和穩定性

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Molecular brain, 6, 19-19 (2013-05-04)
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