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生物源
human plasma
品質等級
形狀
lyophilized
比活性
≥1000 NIH units/mg protein
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
溶解度
water: 1 mg/mL
aqueous buffer: soluble
儲存溫度
−20°C
一般說明
凝血酶是一种钠激活的二型酶，包含两个阴离子结合的外源性位点，即ABE-I和ABE-II。这种丝氨酸蛋白酶由酶原凝血酶原（因子II）在肝脏中合成。
應用
人血浆凝血酶已用于：
- 作为内皮生长培养基（EGM）成分用于卡波氏肉瘤相关疱疹病毒人内皮细胞系（KSHV-HuARLT）小鼠细胞的移植和再分离
- 生产纤维蛋白凝胶
- 作为EGM培养基成分用于KSHV-HuARLT细胞和matrigel植入物的病毒拷贝数分析
生化／生理作用
凝血酶裂解纤维蛋白原，并将其转化为纤维蛋白。然后它激活因子V、VIII、XI和XIII。凝血酶可刺激血小板活化，并稳定纤维蛋白聚合物。它在凝血级联系统的最后阶段起着关键作用。
警告
毒性：有害（C）
單位定義
一个单位是通过与使用生物制品局标准凝血酶生成的标准曲线的比较来测定的。
外觀
从200 mM NaCl、50 mM枸橼酸盐缓冲液、0.1% PEG-8000（pH 6.5）中冷冻干燥。含有BSA作为稳定剂。
準備報告
由经认证测试对HBsAg以及HIV和HCV抗体呈阴性的血浆制备而成。
重構
复溶后，等分并冷冻保存（-70°C）。贮备溶液在-70°C下可稳定保存至多2个月。
分析報告
通过SDS-PAGE从均质凝血酶原完成激活
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
仅供研究使用。在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。
訊號詞
Danger
危險分類
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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