528215

Anti-PAI-1 Mouse mAb (MA-33B8)

liquid, ≥90% (SDS-PAGE), clone MA-33B8

• 别名: Anti-Plasminogen Activator Inihibitor-1
• 分類程式碼代碼: 12352203

属性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: MA-33B8, monoclonal
• 化驗: ≥90% (SDS-PAGE)
• 形狀: liquid
• 不包含: preservative
• 物種活性: rabbit, human
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; avoid repeated freeze/thaw cycles
• 同型: IgG
• 運輸包裝: wet ice
• 儲存溫度: −70°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SERPINE1(5054)

说明

一般說明

Purified mouse monoclonal antibody. Recognizes the ~50 kDa PAI-1 protein.

Recognizes the ~50 kDa PAI-1 protein.

This Anti-PAI-1 Mouse mAb (MA-33B8) is validated for use in Immunoblotting, Neutralization Studies for the detection of PAI-1.

免疫原

Human

human tPA-PAI-1 complex

應用

Immunoblotting (10 µg/ml)

Neutralization Studies (see application references)

包裝

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

外觀

In 100 mM NaCl, 50 mM sodium phosphate buffer, pH 7.4.

重構

Following initial thaw, aliquot and freeze (-20°C).

其他說明

Montes, R., et al. 2000. Thromb. Haemost.84, 65.
Verhamme, I., et al. 1999. J. Biol. Chem.274, 17511.
Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta1337, 257.

Rapidly inactivates PAI-1 (Plasminogen Activator Inhibitor-1) to the latent form. Like the native latent form, PAI-1 inactivated by antibody was protected from cleavage by elastase. Also shown to reduce renal fibrin deposits in a rabbit model of endotoxemia. Variables associated with assay conditions will dictate the proper working dilution.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable