444218

MMP-3 Inhibitor I

The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• 别名: MMP-3 Inhibitor I, Ac-RCGVPD-NH₂, Stromelysin-1 Inhibitor
• 经验公式（希尔记法）: C₂₇H₄₆N₁₀O₉S
• 分子量: 686.78
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥90% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic)
• 顏色: white
• 溶解度: water: 1 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

Inhibits matrix metalloproteinase-3 (stromelysin) (IC₅₀ = 5 µM). The inhibitor is based on a segment from the conserved region of the NH₂-terminal propeptide domain.

Inhibits the matrix metalloproteinase MMP-3 (IC₅₀ = 5 µM).

生化／生理作用

Cell permeable: no

Primary Target
MMP-3

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 5 µM against MMP-3

警告

Toxicity: Standard Handling (A)

序列

Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂

外觀

Supplied as a trifluroacetate salt.

重構

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.

其他說明

Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable