product name
巴马司他, ≥98% (HPLC)
化驗
≥98% (HPLC)
形狀
powder
顏色
white to tan
溶解度
DMSO: ≥15 mg/mL
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc2cccs2)C(=O)NO
InChI
1S/C23H31N3O4S2/c1-15(2)12-17(18(22(28)26-30)14-32-20-10-7-11-31-20)21(27)25-19(23(29)24-3)13-16-8-5-4-6-9-16/h4-11,15,17-19,30H,12-14H2,1-3H3,(H,24,29)(H,25,27)(H,26,28)/t17-,18+,19+/m1/s1
InChI 密鑰
XFILPEOLDIKJHX-QYZOEREBSA-N
應用
巴马司他已在多种研究中被用于抑制基质金属蛋白酶（MMP）的活性。
生化／生理作用
巴马司他是基质金属蛋白酶（MMP）的异羟肟酸类抑制剂。它抑制小鼠模型中肺肿瘤的生长和扩散，乳腺癌再生和人结肠肿瘤的生长和扩散。巴马司他降低 MMP 介导的血管功能障碍和血管壁损伤，并增强牙科粘合剂的密封性能和粘合强度。
巴马司他是一种有效的广谱基质金属蛋白酶（MMP）抑制剂。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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