推荐产品
生物源
rabbit
品質等級
抗體表格
affinity purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
chicken, human, mouse
製造商／商標名
Upstate®
技術
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
phosphorylation (pTyr418)
基因資訊
human ... SRC(6714)
特異性
Predicted to cross-react with Rat and Frog (100% homologous) based on sequence homology.
Recognizes Src phosphorylated on Tyrosine residue 418.
免疫原
Peptide corresponding to amino acid region encompassing the human, mouse, rat, chicken, and frog phospho-Src (Tyr418)
應用
Anti-phospho-Src (Tyr418) Antibody detects level of phospho-Src (Tyr418) & has been published & validated for use in IC, IH & WB.
Immunoblot Analysis: 1:1000 dilutions of this lot detected phospho-Src (Tyr418) in RIPA lysate of Src transfected CEF cells.
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
品質
Routinely evaluated by immunoblot.
標靶描述
60 kDa
外觀
ImmunoAffinity Purified
Affinity Purified rabbit polyclonal IgG in PBS (without Mg2+ and Ca2+), pH 7.3 containing 0.5 mg/mL BSA (IgG, protease free) and 0.025% sodium azide and 50% glycerol.
儲存和穩定性
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析報告
Control
Chick embryo fibroblast (CEF) cells expressing human wild-type Src protein
Chick embryo fibroblast (CEF) cells expressing human wild-type Src protein
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Aida Habibovic et al.
JCI insight, 1(18), e88811-e88811 (2016-11-05)
Chronic inflammation with mucous metaplasia and airway remodeling are hallmarks of allergic asthma, and these outcomes have been associated with enhanced expression and activation of EGFR signaling. Here, we demonstrate enhanced expression of EGFR ligands such as amphiregulin as well
Functional stability of a mixed microbial consortium producing PHA from waste carbon sources.
Erik R Coats,Frank J Loge,William A Smith,David N Thompson,Michael P Wolcott
Applied Biochemistry and Biotechnology null
Src: regulation, role in human carcinogenesis and pharmacological inhibitors.
Tsygankov, A Y and Shore, S K
Current Pharmaceutical Design, 10, 1745-1756 (2004)
c-Src and cooperating partners in human cancer
Ishizawar, Rumey and Parsons, Sarah J
Cancer Cell, 6, 209-214 (2004)
Shinkyu Choi et al.
Antioxidants & redox signaling, 30(4), 505-519 (2018-01-18)
Altered redox state has been related to the development of normal pregnancy (NP) and preeclampsia (PE). Endothelial KCa2.3 and KCa3.1 (KCas) play an important role in vasodilation, and KCas levels are affected by oxidative stress. We investigated the mechanisms of
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