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Merck

T-907

Supelco

替马西泮标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

别名:

Temazepam Standard Solution

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About This Item

经验公式(希尔记法):
C16H13ClN2O2
分子量:
300.74
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material

品質等級

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

格式

single component solution

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

CN1C(=O)C(O)N=C(c2ccccc2)c3cc(Cl)ccc13

InChI

1S/C16H13ClN2O2/c1-19-13-8-7-11(17)9-12(13)14(18-15(20)16(19)21)10-5-3-2-4-6-10/h2-9,15,20H,1H3

InChI 密鑰

SEQDDYPDSLOBDC-UHFFFAOYSA-N

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一般說明

替马西泮,商品名为Restoril®和Normison,是批准用于短期治疗失眠的苯二氮卓类药物。该药物具有抗焦虑、抗惊厥和骨骼肌松弛特性。该认证Snap-N-Spike®溶液适用于各种 LC/MS 或 GC/MS 应用,包括从法医分析和止痛药处方检测到临床毒理学和尿液药物测试。

應用


  • Evaluation of an activated carbon disposal system: This study evaluates an activated carbon disposal system for safely disposing of model prescription sedative medications, including Temazepam, focusing on the environmental aspects and the prevention of medication abuse (Dasht Bozorg et al., 2020).

  • Rapid determination of benzodiazepines in pharmaceuticals: Research on the rapid determination of benzodiazepines, including Temazepam, using surface-enhanced Raman scattering demonstrates potential applications in the identification of counterfeit pharmaceuticals (Kimani et al., 2021).

  • Biologically active benzodiazepine metabolites: A study on the formation of biologically active benzodiazepine metabolites in hydroponic conditions used Arabidopsis thaliana cell cultures to explore environmental and pharmacological impacts, relevant to Temazepam research (Dudley et al., 2019).

  • Racemization of chiral 1,4-benzodiazepines: Investigation into the racemization of oxazepam and other 1,4-benzodiazepines in aqueous solution provides insights into the stability and behavior of these compounds, which includes Temazepam, under laboratory conditions (Hok et al., 2019).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Restoril is a registered trademark of Mallinckrodt Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


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实验方案

To optimize hydrolysis using β-glucuronidase, factors such as incubation time, temperature, hydrolysis pH, enzyme source, and enzyme concentration must be evaluated for each glucuronide metabolite to be analyzed.

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