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P-055

Supelco

普萘洛尔 盐酸盐 溶液

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式（希尔记法）:
C16H21NO2·HCl
CAS号:
318-98-9
分子量:
295.80
EC號碼:
200-659-6
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

濃度

1.0 mg/mL in methanol (as free base)

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

格式

single component solution

儲存溫度

−20°C

SMILES 字串

Cl.CC(C)NCC(O)COc1cccc2ccccc12

InChI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

InChI 密鑰

ZMRUPTIKESYGQW-UHFFFAOYSA-N

基因資訊

human ... ADRB1(153) , ADRB2(154)

相关类别

一般說明

一种经认证的参比溶液，适用于临床和诊断测试、尿液药物测试、法医分析或临床毒理学的LC/MS或GC/MS测试方法的校准器和控制的起始材料。普萘洛尔是一种交感神经非选择性受体阻滞剂，用于治疗高血压、焦虑和恐慌等多种疾病。该药物以Inderal®、Avlocardyl、Deralin和Dociton等许多商品名出售。

應用

<ul>
<li><strong>Propranolol hydrochloride solution for infantile hemangioma:</strong>Liposomal formulations of propranolol hydrochloride have been developed for the treatment of infantile hemangioma, offering a targeted therapeutic approach in pediatric dermatology (Nifli et al., 2024).</li>
<li><strong>Propranolol hydrochloride:</strong> Research on the percutaneous absorption of solvent-deposited propranolol hydrochloride across different skin layers provides insights into its properties like it can be used as a function of dose and ionization state and as a calibration standard (Tonnis et al., 2024).</li>
</ul>

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Inderal is a registered trademark of Cranford Pharmaceuticals, LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

分析证书(COA)

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Amy C Arnold et al.
Neurology, 80(21), 1927-1933 (2013-04-26)
To determine the effect of low-dose propranolol on maximal exercise capacity in patients with postural tachycardia syndrome (POTS). We compared the effect of placebo vs a single low dose of propranolol (20 mg) on peak oxygen consumption (VO2max), an established
[Hemangioma can be effectively treated with propranolol. Experiences from twelve cases, with promising results and few side effects].
Carl Johan Rosenkvist et al.
Lakartidningen, 110(19-20), 942-945 (2013-06-12)
Practice gaps. Propranolol to treat hemangiomas of infancy: safety and side effect recognition.
Jonathan A Dyer
JAMA dermatology, 149(4), 485-486 (2013-05-30)
Patricia Mabel Pintos et al.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 65(1), 39-51 (2013-06-12)
Propranolol (P) treatment exerts a preventive effect against the detrimental consequences to bone status in mildly chronically food-restricted growing rats (NGR) by an increment in cortical bone and by improving its spatial distribution. To study the effect of beta-blocker on
Jun Zhang et al.
Rapid communications in mass spectrometry : RCM, 27(7), 731-737 (2013-03-16)
Multiplexed liquid chromatography (LC) coupled with multiple-injection-chromatogram acquisition has emerged as the method of choice for high-speed discovery bioanalysis, because it significantly reduces injection-to-injection cycle time while maintaining the chromatography quality. Historically, systems utilizing this approach had been custom built
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