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Merck

I5627

Sigma-Aldrich

异丙肾上腺素 盐酸盐

≥98.5% (TLC), powder, β-adrenoceptor agonist

别名:

(±)-异丙肾上腺素 盐酸盐, 1-(3′,4′-二羟基苯基)-2-异丙基氨基乙醇 盐酸盐, N-异丙基-DL-去甲肾上腺素 盐酸盐

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About This Item

经验公式(希尔记法):
C11H17NO3 · HCl
CAS号:
分子量:
247.72
Beilstein:
3917363
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

产品名称

异丙肾上腺素 盐酸盐,

品質等級

mp

165-175 °C (dec.) (lit.)

起源

Sanofi Aventis

SMILES 字串

Cl.CC(C)NCC(O)c1ccc(O)c(O)c1

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI 密鑰

IROWCYIEJAOFOW-UHFFFAOYSA-N

基因資訊

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生化/生理作用

β-肾上腺素受体激活剂;增加胞质cAMP。

特點和優勢

该化合物在受体分类和信号转导手册中β-肾上腺素能受体页面中进行了详细介绍。想要浏览手册的其他页面, 请单击此处
该化合物是由Sanofi Aventis研发。想要浏览其他由制药公司开发的化合物以及已批准物/候选药物清单, 请单击此处

其他說明

仅供研究使用

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Aaron M Ring et al.
Nature, 502(7472), 575-579 (2013-09-24)
G-protein-coupled receptors (GPCRs) are integral membrane proteins that have an essential role in human physiology, yet the molecular processes through which they bind to their endogenous agonists and activate effector proteins remain poorly understood. So far, it has not been
Michael Schwarzl et al.
Critical care medicine, 41(12), e401-e410 (2013-08-22)
We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. Randomized controlled prospective experimental study. Large animal facility, Medical University of Graz, Austria. Thirteen anesthetized and mechanically ventilated pigs. Lipopolysaccharide was administered for 4 hours. With
Jiao Li et al.
PloS one, 8(3), e58334-e58334 (2013-03-28)
Here we investigate how ß-adrenergic stimulation of the heart alters regulation of ryanodine receptors (RyRs) by intracellular Ca(2+) and Mg(2+) and the role of these changes in SR Ca(2+) release. RyRs were isolated from rat hearts, perfused in a Langendorff
Eric M Jones et al.
eLife, 9 (2020-10-22)
The >800 human G protein-coupled receptors (GPCRs) are responsible for transducing diverse chemical stimuli to alter cell state- and are the largest class of drug targets. Their myriad structural conformations and various modes of signaling make it challenging to understand
Sander Land et al.
Biophysical journal, 104(6), 1349-1356 (2013-03-27)
Previous studies on Serca2 knockout (KO) mice showed that cardiac function is sustained in vivo for several weeks after knockout, whereas SERCA protein levels decrease and calcium dynamics are significantly impaired. In this study, we reconcile observed cellular and organ

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