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Merck

N-048

Supelco

(±)-烟碱-D4标准液 CRM 溶液

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C10H10N2D4
分子量:
166.26
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

品質等級

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

濃度

100 μg/mL in acetonitrile

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

forensics and toxicology

格式

single component solution

儲存溫度

−20°C

SMILES 字串

[2H]c1nc([2H])c(c([2H])c1[2H])C2CCCN2C

InChI

1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/i2D,4D,6D,8D

InChI 密鑰

SNICXCGAKADSCV-MNYIHESISA-N

一般說明

一种稳定标记的内标,适用于尼古丁水平的定量分析,可用于法医分析、尼古丁检测、临床和诊断检测、尿液药物检测、或LC/MS或GC/MS同位素稀释方法。尼古丁是一种高度添加的烟草生物碱,与许多健康风险相关,如心脏健康、心理健康和癌症。

應用


  • Standard for metabolic and pharmacokinetic studies: (±)-Nicotine-d₄ solution is extensively used as a stable isotope-labeled standard in metabolic and pharmacokinetic research. It aids in tracing nicotine metabolism and understanding its dynamics within biological systems, crucial for developing targeted therapies in nicotine addiction (Kintz et al., 1998).



法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

FlameExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

35.6 °F - closed cup

閃點(°C)

2 °C - closed cup


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Rama Krishna Nimmakayala et al.
Gastroenterology, 155(3), 892-908 (2018-06-05)
Cigarette smoking is a major risk factor for pancreatic cancer. Aggressive pancreatic tumors contain cancer cells with stem cell features. We investigated whether cigarette smoke induces stem cell features in pancreatic cancer cells. KrasG12D; Pdx1-Cre mice were exposed to cigarette

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