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E-075

Supelco

雌酚酮 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式（希尔记法）:
C18H22O2
CAS号:
53-16-7
分子量:
270.37
MDL號碼:
MFCD00003620
分類程式碼代碼:
41116107
PubChem物質ID:
329798986
NACRES:
NA.24

等級

certified reference material

品質等級

300

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing
clinical testing

格式

single component solution

儲存溫度

−20°C

SMILES 字串

CC12CCC3C(CCc4cc(O)ccc34)C1CCC2=O

InChI

1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1

InChI 密鑰

DNXHEGUUPJUMQT-CBZIJGRNSA-N

基因資訊

human ... ESR1(2099)

相关类别

一般說明

通过LC-MS/MS或GC/MS监测血清或血浆中雌二醇，雌酮的前体，以评估和诊断女性的发育异常，酶失活或缺乏，多囊卵巢综合征（PCOS）或激素替代疗法。

應用


  • Fluconazole solution for yeast infection treatment: Fluconazole is extensively utilized for its efficacy against yeast infections, specifically vulvovaginal candidiasis. It operates by inhibiting the synthesis of ergosterol, crucial for fungal cell membrane integrity, thereby exerting its antifungal effects (Picheta et al., 2024).

  • Antifungal medication in systemic candidiasis: Fluconazole solution is critical in treating systemic candidiasis, offering a potent antifungal mechanism that disrupts the fungal cell membrane′s ergosterol content, essential for maintaining fungal cell viability (Dettlaff et al., 2024).

  • Fluconazole in vitro antifungal activity assay development: Fluconazole is utilized in the development of in vitro antifungal activity assays, which are crucial for screening potential antifungal agents and assessing their efficacy against various fungal pathogens (Teba et al., 2024).


法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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E-074

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E-076

17α-乙炔基雌二醇 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

H-126

16α-羟雌酮, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

E-117

17β-雌二醇--13C3标准液 溶液, 10 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

H-127

2-羟雌酮 溶液, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

分析证书(COA)

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Kiyoshi Ito
The Tohoku journal of experimental medicine, 212(1), 1-12 (2007-04-28)
Hormone replacement therapy (HRT) has become available over the past few decades, but the risk of breast cancer with HRT remains controversial. The Women's Health Initiative Study has recently demonstrated that women receiving estrogen plus progestin (HRT) have an increased
Susannah J Stanway et al.
The oncologist, 12(4), 370-374 (2007-05-02)
Inhibitors of steroid sulfatase are being developed as a novel therapy for hormone-dependent breast cancer in postmenopausal women. Data suggest that steroid sulfatase (STS) activity is much higher than aromatase activity in breast tumors and high levels of STS mRNA
Ghada N Farhat et al.
Journal of the National Cancer Institute, 105(19), 1496-1503 (2013-09-18)
Although high endogenous sex hormone levels and estrogen plus progestin (E+P) therapy are associated with increased breast cancer risk, it is unknown whether pretreatment levels of sex hormones modify E+P effect on breast cancer. We conducted a nested case-control study
Xavier Remesar et al.
Medicinal research reviews, 32(6), 1263-1291 (2011-02-03)
Oleoyl-estrone (OE) is a powerful slimming agent that is also present in plasma and adipose tissue, where it is synthesized. It acts through the formation of a derivative W. OE effects (and W levels) are proportional to the dose. OE
Eva Fetter et al.
Aquatic toxicology (Amsterdam, Netherlands), 154, 221-229 (2014-06-14)
Xenoestrogens may persist in the environment by binding to sediments or suspended particulate matter serving as long-term reservoir and source of exposure, particularly for organisms living in or in contact with sediments. In this study, we present for the first
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