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等級
certified reference material
品質等級
形狀
liquid
特點
SNAP-N-SPIKE®, SNAP-N-SHOOT®
包裝
ampule of 1 mL
製造商/商標名
Cerilliant®
濃度
1.0 mg/mL in acetonitrile
技術
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
應用
clinical testing
形式
single component solution
儲存溫度
−20°C
SMILES 字串
O=C1C=C2CCC3C4C(C(CC4)=O)(C)CCC3C2(C)CC1
InChI
1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3
InChI 密鑰
AEMFNILZOJDQLW-UHFFFAOYSA-N
一般說明
雄烯二酮是产生睾酮、雌酮和雌二醇的生化途径中的激素和中间体。该经认证的加标溶液®适用于作为线性标准品、校准品和质控品的起始物料,用于内分泌学、临床化学、新生儿筛查和运动测试中的许多LC/MS和GC/MS应用。
應用
<ul>
<li><strong>类固醇生物合成研究:</strong>该研究重点介绍了雄烯二酮溶液在液相色谱-串联质谱法干血斑分析中的实用性,提供了一种新生儿先天性肾上腺增生和其它类固醇相关疾病的筛查方法(Zhan et al., 2022)。</li>
<li><strong>激素前体生化研究:</strong>研究人员开发了一种使用液相色谱-串联质谱法同时测定人血清中睾酮、雄烯二酮和脱氢表雄酮的方法,该方法为激素生物合成和代谢的研究提供了支持(Xu et al., 2017)。</li>
<li><strong>合成代谢类固醇研究:</strong>关于应用UHPLC-MS/MS方法来测定马血清中17种类固醇激素(包括雄烯二酮)的研究,对于推进兴奋剂和生理学研究至关重要(Genangeli et al., 2017)。
</ul>
<li><strong>类固醇生物合成研究:</strong>该研究重点介绍了雄烯二酮溶液在液相色谱-串联质谱法干血斑分析中的实用性,提供了一种新生儿先天性肾上腺增生和其它类固醇相关疾病的筛查方法(Zhan et al., 2022)。</li>
<li><strong>激素前体生化研究:</strong>研究人员开发了一种使用液相色谱-串联质谱法同时测定人血清中睾酮、雄烯二酮和脱氢表雄酮的方法,该方法为激素生物合成和代谢的研究提供了支持(Xu et al., 2017)。</li>
<li><strong>合成代谢类固醇研究:</strong>关于应用UHPLC-MS/MS方法来测定马血清中17种类固醇激素(包括雄烯二酮)的研究,对于推进兴奋剂和生理学研究至关重要(Genangeli et al., 2017)。
</ul>
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
35.6 °F - closed cup
閃點(°C)
2 °C - closed cup
其他客户在看
S N Schauer et al.
Theriogenology, 79(3), 409-416 (2012-12-04)
There is evidence in several species that high circulating LH concentrations can interfere with normal follicle development and ovulation. In the mare, high LH levels after induction of luteolysis with PGF(2α) have been temporally associated with an increased incidence of
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BioMed research international, 2013, 301540-301540 (2013-03-14)
Bone marrow stem cells (BMSCs) have the capacity to differentiate into mature cell types of multiple tissues. Thus, they represent an alternative source for organ-specific cell replacement therapy in degenerative diseases. In this study, we demonstrated that female rat BMSCs
Ewa Łucja Gregoraszczuk et al.
Reproduction (Cambridge, England), 145(3), 311-317 (2013-04-13)
Evidence from both clinical and animal studies suggests that exposure to excess androgens results in cyst formation. The present in vitro study assessed the effects of supraphysiological concentrations of leptin (20 and 40 ng/ml) on progesterone (P(4)), androstenedione androstendione (A(4))
Hidetaka Tasaki et al.
Theriogenology, 79(5), 809-814 (2013-01-26)
Antrum formation and estradiol (E2) secretion occur during early folliculogenesis. The objective was to determine the role of E2 in antrum formation of oocyte-granulosa cell complexes (OGCs) derived from porcine preantral follicles (PAFs). Supplementation of the culture medium with E2
Floriane Guibert et al.
Proceedings. Biological sciences, 280(1753), 20122368-20122368 (2012-12-21)
The prenatal environment is a source of phenotypic variability influencing the animal's characteristics. Prenatal stress affects not only the development of offspring, but also that of the following generation. Such effects have been best documented in mammals but can also
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