SML2364

4-雄烯-3,17-二酮

≥98% (HPLC)

• 别名: 雄烯二酮
• 经验公式（希尔记法）: C₁₉H₂₆O₂
• CAS号: 63-05-8
• 分子量: 286.41
• Beilstein: 2059239
• MDL號碼: MFCD00003615
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 藥物控制: USDEA Schedule III
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: room temp
• SMILES 字串: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)C(=O)CC[C@@]24[H]
• InChI: 1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
• InChI 密鑰: AEMFNILZOJDQLW-QAGGRKNESA-N

说明

生化／生理作用

睾酮前体和具有雄激素活性的代谢物；可增大前列腺癌或胰腺癌的风险。

4-Androstenedione, commonly known as Androstenedione, is an endogenous androgen steroid hormone. 4-Androstenedione functions as an intermediate in the biosynthesis of testosterone, estradiol and estrone. Recent studies indicate that 4-Androstenedione is involved in aromatase inhibitors induce painful musculoskeletal symptoms (AIMSS) by activation of TRPA1.

安全信息

• 象形圖: GHS08,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H351,H360FD,H362
• 防範說明: P202 - P260 - P263 - P264 - P301 + P312 - P308 + P313
• 危險分類: Acute Tox. 4 Oral - Carc. 2 - Lact. - Repr. 1A
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 2