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Merck

E-070

Supelco

依维莫司-D4 溶液

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C53H79NO14D4
分子量:
962.25
EC號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

品質等級

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

濃度

100 μg/mL in acetonitrile

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

形式

single component solution

儲存溫度

−70°C

SMILES 字串

[2H]C([2H])(O)C([2H])([2H])OC1CCC(CC(C)C2CC(=O)C(C)\C=C(C)\C(O)C(OC)C(=O)C(C)CC(C)\C=C\C=C\C=C(C)\C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC)CC1OC

InChI

1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/i24D2,25D2

InChI 密鑰

HKVAMNSJSFKALM-ULVVDLMCSA-N

一般說明

免疫抑制剂依维莫司的稳定标记内标,以Zortress®和Certican的形式销售,用于器官移植,以Afinitor®的形式销售,用于肾癌和胰腺癌的治疗。临床实验室使用LC-MS/MS定量患者全血样本中的依维莫司水平。虽然许多依维莫司LC-MS/MS方法使用32-去甲氧基雷帕霉素或子囊霉素作为内标物,但分析中可能会出现较高水平的变异性/较低水平的可再现性以及潜在的干扰。使用稳定标记的依维莫司类似物是减少LC-MS/MS分析可变性或减轻潜在干扰的最佳选择。

法律資訊

Afinitor is a registered trademark of Novartis AG
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Zortress is a registered trademark of Novartis AG

象形圖

FlameExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

35.6 °F - closed cup

閃點(°C)

2 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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