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化驗
>99% (TLC)
形狀
powder
包裝
pkg of 2 × 100 mg (840053P-200mg)
pkg of 1 × 25 mg (840053P-25mg)
製造商／商標名
Avanti Research™ - A Croda Brand 840053P
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
InChI 密鑰
WTJKGGKOPKCXLL-VYOBOKEXSA-N
一般說明
Phosphatidylcholine (PC) is an important structural component of cell membrane and plasma lipoprotein. It is synthesized by CDP choline pathway. Liver is the main site for the synthesis of PC. Brain PC predominantly contains PC 16:0/16:0 and PC 16:0/18:1.
應用
Brain PC is suitable for use:
- in the preparation of small unilamellar vesicles (SUVs)
- as a constituent in serial protein misfolding cyclic amplification (sPMCA) buffer
- as standard for ion mobility shift-mass spectrometry (IMS-MS)
生化／生理作用
Phosphatidylcholine (PC) is the major source of choline through food supplements. PC helps in improving learning and memory. PC functions in membrane fusion and transport and endocytosis. It is implicated in lowering of blood lipid and cholesterol levels, preventing cardiovascular disease and inhibiting obesity.
包裝
5 mL Clear Glass Sealed Ampule (840053P-200mg)
5 mL Clear Glass Sealed Ampule (840053P-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
Using supported bilayers to study the spatiotemporal organization of membrane-bound proteins.
Methods in Cell Biology, 128, 223-241 (2015)
The membrane lipid phosphatidylcholine is an unexpected source of triacylglycerol in the liver.
van der Veen JN, et al.
The Journal of Biological Chemistry, 287(28), 23418-23426 (2012)
Choline, Phospholipids, Health, and Disease (1998)
Requirements for mutant and wild-type prion protein misfolding in vitro.
Noble GP, et al.
Biochemistry, 54(5), 1180-1187 (2015)
Effects of different fatty acids composition of phosphatidylcholine on brain function of dementia mice induced by scopolamine.
Zhou MM, et al.
Lipids in Health and Disease, 15(1), 135-135 (2016)
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