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主要文件

810222C

Avanti

C6-NBD Glucosyl Ceramide

Avanti Research - A Croda Brand 810222C

别名:

N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-glucosyl-β1-1′-sphingosine

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About This Item

经验公式(希尔记法):
C36H59N5O11
CAS号:
分子量:
737.88
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (810222C-250ug)
pkg of 1 × 1 mg (81022C-1MG)

製造商/商標名

Avanti Research - A Croda Brand 810222C

濃度

0.25 mg/mL (810222C-250ug)

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

C6-NBD Glucosyl Ceramide is a fluorescent derivative of biologically active compound, glucosyl ceramide. Glucosyl ceramide belongs to the class of sphingolipids that are synthesized in the cis/medial-Golgi apparatus by the glycosylation of ceramide.

應用

C6-NBD Glucosyl Ceramide may be used as a substrate for glucocerebrosidase (GCase) activity assay in Drosophila melanogaster and mice.

生化/生理作用

Glucosylceramide is the precursor of different glycosphingolipids including gangliosides and sulfatides. Glucosyl ceramide is also known to be responsible for axon growth of neural cells. The accumulation of glucosyl ceramide is associated with an inherited lysosomal storage disorder, Gaucher′s disease.

包裝

5 mL Amber Glass Screw Cap Vial (81022C-1MG)
5 mL Clear Glass Sealed Ampule (810222C-250ug)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system

水污染物質分類(WGK)

WGK 3


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H Zhao et al.
Cellular and molecular life sciences : CMLS, 59(4), 694-707 (2002-05-23)
Gaucher disease is an autosomal recessive trait and the most common lysosomal storage disease. The pathogenesis evolves from the diminished activity of the lysosomal hydrolase, acid beta-glucosidase and the resultant accumulation of glucosylceramide within lysosomes. The pathogenic mechanisms are poorly

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