跳转至内容
Merck
所有图片(2)

Key Documents

View All Documentation

700071P

Avanti

24(R)-hydroxycholesterol

Avanti Research™ - A Croda Brand

别名:

5-cholestene-3β,24-diol  ; 24-hydroxycholest-5-en-3-ol

登录查看公司和协议定价
所有图片(2)

About This Item

经验公式（希尔记法）:
C27H46O2
CAS号:
27460-26-0
分子量:
402.65
分類程式碼代碼:
12352211
NACRES:
NA.25

描述

cholest-5-ene-3β,24(R)-diol

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (700071P-1mg)

製造商／商標名

Avanti Research™ - A Croda Brand

運輸包裝

dry ice

儲存溫度

−20°C

相关类别

一般說明

24-hydroxycholesterol (24-OH) is an oxidized product of cholesterol. It is synthesized in the presence of enzyme 24S-hydroxylase (CYP46A1).

生化／生理作用

24(S)-hydroxycholesterol is preferred over 24(R)-hydroxycholesterol by human 7α-hydroxylase. However, the porcine enzyme is active towards both isomers. 24-hydroxycholesterol (24-OH) favors sirtuin 1 expression and reduces the tau protein phosphorylation.

包裝

5 mL Amber Glass Screw Cap Vial (700071P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

No data available

閃點（°C）

No data available

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Gabriella Testa et al.
Redox biology, 17, 423-431 (2018-06-09)
It is now established that cholesterol oxidation products (oxysterols) are involved in several events underlying Alzheimer's disease (AD) pathogenesis. Of note, certain oxysterols cause neuron dysfunction and degeneration but, recently, some of them have been shown also to have neuroprotective

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门