219399

Cathepsin D Substrate I

Useful as a substrate for the determination of cathepsin D activity.

• 别名: Cathepsin D Substrate I, Bz-RGFFP-4-MeOβNA, HCl
• 经验公式（希尔记法）: C₄₉H₅₅N₉O₇ · xHCl
• 分子量: 882.02 (free base basis)
• 分類程式碼代碼: 51111800
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: lyophilized solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated; protect from light
• 顏色: white
• 溶解度: DMSO: 5 mg/mL
• 螢光: λ_ex ~345 nm; λ_em ~425 nm
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

A useful substrate for colorimetric or fluorometric assay of cathepsin D activity. Cathepsin D hydrolyzes the Phe-Phe bond. Dipeptidyl aminopeptidase II is required to free the 4-methoxy-β-naphthylamine (4MβNA). Excitation max: ~345 nm; emission max: ~425 nm.

Useful as a substrate for the determination of cathepsin D activity. Suitable for either colorimetric or fluorometric assay. Cathepsin D hydrolyzes the Phe-Phe bond. Requires dipeptidyl aminopeptidase II to free 4-methoxy-β-naphthylamine (4MeOβNA).

生化／生理作用

Cell permeable: no

Primary Target
Substrate for the determination of cathepsin D activity

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

序列

Bz-Arg-Gly-Phe-Phe-Pro-4MeOβNA, HCl

其他說明

Takahashi, T., and Tang, J. 1981. Methods Enzymol.80, 565.
Smith, R.E., and Van Frank, R.M. 1975. in Lysosomes in Biology and Pathology4 (Dingle, J.T., and Dean, R.T., eds.) p. 193, American Elsevier, Holland.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable