QBD10773

dPEG^®₂₄-biotin acid

>95% (HPLC)

• 别名: Biotin-PEG-acid, Biotin-PEG₂₄-COOH, PEG₁₀₀₀ biotin acid, PEG₂₄-biotin acid
• 经验公式（希尔记法）: C₆₁H₁₁₇N₃O₂₈S
• 分子量: 1372.65
• MDL號碼: MFCD26793761
• 分類程式碼代碼: 12352106
• NACRES: NA.22

属性

• 化驗: >95% (HPLC)
• 形狀: solid or viscous liquid
• 反應適用性: reaction type: Biotinylations; reaction type: Pegylations
• 聚合物結構: shape: linear; functionality: monofunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

特點和優勢

dPEG₂₄ biotin acid consists of a biotin molecule conjugated to a single molecular weight polyethylene glycol chain of discrete length (dPEG). The dPEG chain is 76 atoms (90.1 Å) long. The distal end of the dPEG chain terminates with a propionic acid group. The terminal acid is available for direct conjugation to free amines or functionalization as an active ester. Amphiphilic dPEG₂₄ biotin acid can be dissolved both in water or aqueous buffer and in organic solvent. It does not cause aggregation or precipitation of biomolecules. Using 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) chemistry, dPEG₂₄ biotin acid can be coupled directly to free primary amines in aqueous media. These free amines can be on a protein, peptide, or the treated surface of a nanoparticle. Moreover, the acid moiety can be functionalized with other reactive groups for coupling directly to surfaces such as glass, gold, or magnetic nanoparticles. The linker length of dPEG₂₄ biotin acid is much longer than the linker lengths of LC-biotin and of LC-LC-biotin and is a monodisperse equivalent of a PEG₁₀₀₀. The performance characteristics of dPEG₂₄-biotin acid are quite superior to both LC-biotin and LC-LC-biotin.

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法律資訊

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable