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Merck

764620

Sigma-Aldrich

Poly(D,L-lactide)

greener alternative

average Mn 10,000, PDI ≤1.2

别名:

PDLA, PLA, polyDL-lactide

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About This Item

分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

solid

光學活性

[α]/D 0°, c = 0.5% in chloroform

分子量

average Mn 10,000

環保替代產品特色

Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

降解時間

<6 months

mp

287-293 °C

蛋白質二硫鍵異構酶

≤1.2

環保替代類別

儲存溫度

2-8°C

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一般說明

We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This is an enabling product that belongs to a family of high-performance bio-based polymers that are essential for developing efficient, low-cost, and environmentally friendly renewable energy solutions. Click here for more information.

應用

Used in Drug Delivery including coating nanoparticles1. Can be end-group functionalizated2 or used as a macroinitiator/block precursor3.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

商品

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

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