推荐产品
化驗
97%
mp
64-66 °C (lit.)
儲存溫度
−20°C
SMILES 字串
C1CCN(CC1)C2CCNCC2
InChI
1S/C10H20N2/c1-2-8-12(9-3-1)10-4-6-11-7-5-10/h10-11H,1-9H2
InChI 密鑰
QDVBKXJMLILLLB-UHFFFAOYSA-N
基因資訊
rat ... Grin2a(24409)
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應用
Reactant for synthesis of:
Arylthiadiazole H3 antagonists
Water-soluble N-mustards as anticancer agents
Antitubercular drugs
Vasopressin1b receptor antagonists
MDR modulators
Selective Norepinephrine transporter inhibitors
Arylthiadiazole H3 antagonists
Water-soluble N-mustards as anticancer agents
Antitubercular drugs
Vasopressin1b receptor antagonists
MDR modulators
Selective Norepinephrine transporter inhibitors
药物化学试剂。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Synlett, 8, 1192-1194 (2003)
Journal of medicinal chemistry, 47(1), 101-109 (2003-12-30)
A variety of novel heterocyclic compounds having thienoazepine, pyrroloazepine, furoazepine, and thienodiazepine skeletons were synthesized, most of which exhibited potent antagonism of [(3)H]-AVP specific binding in assays using rat liver (V1), rat kidney (V2), human platelet plasma membranes, and recombinant
European journal of medicinal chemistry, 38(3), 265-275 (2003-04-02)
New antiprotozoals active against Philasterides dicentrarchi, the causative agent of scuticociliatosis in farmed turbot and Black Sea bass-bream, have been synthesised and tested. The most active compounds posses a piperazine ring, generally N-bonded to the heterocycle, and are the 1,8-naphthyridines
Design and synthesis of RNA-specific groove-binding cations: implications for antiviral drug design.
Journal of medicinal chemistry, 37(8), 1063-1069 (1994-04-15)
As as initial step in the design of structure-specific RNA-interactive molecules as potential antiviral agents, we have focused on the synthesis of molecules that exhibit strong and preferential binding to duplex RNA. A series of polycationic ligands have been synthesized
Bioorganic & medicinal chemistry, 13(19), 5592-5599 (2005-08-09)
We have synthesized a conjugate of cis-4,7,10,13,16,19-docosahexenoic acid (DHA) and 10-hydroxycamptothecin (HCPT), DHA-HCPT. The antitumor activity of DHA-HCPT was evaluated in vitro against L1210 leukemia cells and in experimental animal tumor models including L1210 leukemia, Lewis lung carcinoma, and colon
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