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Merck

512443

Sigma-Aldrich

3-氯-L-酪氨酸

97%

别名:

(2S)-2-Amino-3-(3-chloro-4-hydroxyphenyl)propanoic acid, Monochlorotyrosine

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About This Item

线性分子式:
4-(HO)C6H3(Cl)CH2CH(NH2)CO2H
CAS号:
分子量:
215.63
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.22

化驗

97%

光學活性

[α]24/D −2°, c = 1 in 1 M HCl

反應適用性

reaction type: solution phase peptide synthesis

mp

249 °C (lit.)

應用

peptide synthesis

SMILES 字串

N[C@@H](Cc1ccc(O)c(Cl)c1)C(O)=O

InChI

1S/C9H10ClNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1

InChI 密鑰

ACWBBAGYTKWBCD-ZETCQYMHSA-N

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Jihan Talib et al.
Free radical biology & medicine, 53(1), 20-29 (2012-05-23)
Smokers have an elevated risk of atherosclerosis but the origin of this elevated risk is incompletely defined, though increasing evidence supports a role for the oxidant-generating enzyme myeloperoxidase (MPO). In previous studies we have demonstrated that smokers have elevated levels
J J Provencio et al.
Neurocritical care, 12(2), 244-251 (2009-12-08)
Cerebral vasospasm is a significant cause of morbidity in patients after aneurysmal subarachnoid hemorrhage (aSAH). There are few effective treatments. The search for new treatments has focused predominantly on dilating cerebral blood vessels. Growing evidence supports a role for inflammation
Laetitia Mouls et al.
Proteomics, 9(6), 1617-1631 (2009-03-03)
Protein oxidation is thought to contribute to a number of inflammatory diseases, hence the development of sensitive and specific analytical techniques to detect oxidative PTMs (oxPTMs) in biological samples is highly desirable. Precursor ion scanning for fragment ions of oxidized
Eline Thomson et al.
Free radical biology & medicine, 49(9), 1354-1360 (2010-07-22)
We aimed to determine whether myeloperoxidase (MPO) is the main peroxidase present in the airways of children with cystic fibrosis (CF) and to assess which oxidants it produces and whether they are associated with clinical features of CF. Children with
Joseph I Kang et al.
Chemical research in toxicology, 21(5), 1028-1038 (2008-05-03)
While the last 30 years chronicles an extensive effort to understand the damage to DNA caused by reactive oxygen species (ROS), little research has examined the chemical damage to the histone proteins found in chromatin. Hypochlorous acid (HOCl), the primary

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