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形狀
crystalline
mp
233-235 °C (dec.) (lit.)
SMILES 字串
N[C@@H](Cc1ccc(O)c(c1)[N+]([O-])=O)C(O)=O
InChI
1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1
InChI 密鑰
FBTSQILOGYXGMD-LURJTMIESA-N
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應用
3-硝基-L-酪氨酸已用于:
- 蛋白质印迹分析,定量分析小鼠组织蛋白中的硝基酪氨酸水平
- Murashige–Skoog培养基,用于处理野生型和丝裂原活化蛋白激酶6 (mpk6)-2突变体幼苗,推断一氧化氮(NO)和MPK6在调节有丝分裂微管组织中的功能联系
- 免疫细胞化学
生化/生理作用
3-硝基-L-酪氨酸是一种氧化剂和细胞毒剂。在全身性自免疫疾病患者体内,3-硝基酪氨酸可作为氮自由基改性蛋白质的生物标记物。它是过氧亚硝酸盐介导的氧化损伤的标志物。硝基酪氨酸与乳腺癌患者体内的VEGF-C表达和淋巴结转移有关。3-硝基酪氨酸由氧化/亚硝化压力介导的化学改性(如在肺癌发生中观测到的蛋白质硝化)产生。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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